Results 221 to 230 of about 1,814,083 (253)

Magnetoactive Hydrogels to Probe Curvature‐Directed Endothelial Cell Mechanosensing

Advanced Healthcare Materials, EarlyView.
This work establishes a platform to investigate local curvature as a regulator of endothelial mechanosensing independent of shear stress. Magnetoactive hydrogels enable on‐demand curvature of endothelial monolayers to reproduce tortuosity quantified by clinically established metrics.
Avinava Roy, Grace K. Hinds, Joshua Yu‐Chung Liu, Ziqian Yang, Rishab Yanala, Arina E. Velieva, Claudia Loebel   +6 more
wiley   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Mechanotransduction-Driven Modulation of <i>L</i>-Type Calcium Channels: Roles of Nitric Oxide, S-Nitrosylation, and cGMP in Rat Ventricular Cardiomyocytes. [PDF]

Int J Mol Sci
Kamkina OV, Rodina AS, Kamkin A, Bilichenko AS, Kazansky VE, Zolotareva AD, Zolotarev VI, Shileiko SA, Mitrokhin VM, Mladenov MI.   +9 more
europepmc   +1 more source

Biocompatible Conjugated Electrospinning Nanofibrous Membrane With Self‐Powered Piezoelectric Capacity for Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
A self‐powered PCL/gelatin‐PVDF‐TrFE/MXene conjugated electrospun membrane integrates biocompatibility with enhanced piezoelectric responsiveness. Mechanical deformation is converted into localized electrical signals that stimulate wound‐repair cells proliferation and migration, promote angiogenesis and tissue remodeling, and accelerate full‐thickness ...
Diandian Li, Ke Wu, Yangyang Lu, Qinglan Xia, Jialong Chen, Yifan Zhang, Zhaoyu Chen, Zhiyuan She, Junjin Jie, Juzi Xia, Muran Zhou, Aimei Zhong   +11 more
wiley   +1 more source

Voltage-Gated Calcium Channels and the Parity-Dependent Differential Uterine Response to Oxytocin in Rats. [PDF]

Reprod Sci
Sondgeroth K, Boyman E, Pathare R, Porta M.   +3 more
europepmc   +1 more source

Artemisinin‐Loaded Core‐Shell Microspheres Modulate Histone Lactylation to Remodel the Microenvironment for Cartilage Protection in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng, Jianxin Li, Yuyang Luo, Yisi Liu, Feng Xing, Yingchen Ni, Fengyuan Zhang, Zhicheng Fan, Hua Xu, Weidong Zhang, Youhua Wang   +10 more
wiley   +1 more source

Cilnidipine: An L- and N-Type Blocker of Calcium Channels Ameliorating Renal Damage in Experimental Hypertensive Rats. [PDF]

Cureus
Banu Shaikh G, Das KK.
europepmc   +1 more source

Calcium Channels, Clustering, and Single-Amino Acid Control of Blood Pressure and Blood Flow. [PDF]

J Am Heart Assoc
Jensen LJ.
europepmc   +1 more source

The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels. [PDF]

Mol Brain
Antunes FTT, Gadotti VM, Zamponi GW.
europepmc   +1 more source

Using Localization Microscopy to Quantify Calcium Channels at Presynaptic Boutons. [PDF]

Bio Protoc
Mueller BD, Merrill SA, Von Diezmann L, Jorgensen EM.   +3 more
europepmc   +1 more source