Results 201 to 210 of about 652,107 (224)

Bystander effect triggered by calcium electroporation, bleomycin electrotransfer and irreversible electroporation

2022
Electroporation is a method used for local cancer therapy in a form of electrochemotherapy or electroablation [1]. The mechanism of electrochemotherapy is triggered by the process of reversible electroporation; when high intensity electric field increase transmembrane potential of affected cells to a critical value.
Barauskaitė-Šarkinienė, Neringa, Ruzgys, Paulius, Novickij, Vitalij, Šatkauskas, Saulius   +3 more
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Calcium electroporation efficiency dependence on calcium concentration and administration time [PDF]

, 2019
Calcium ion distribution between extra and intracellular compartments plays a crucial role in cellular response to various external stress conditions. Necrotic and apoptotic processes are associated with intracellular calcium ion overload, because once calcium ions reach their threshold in the cytoplasm they cause changes in activity of enzymes ...
Navickaitė, Diana, Ruzgys, Paulius, Maciulevičius, Martynas, Chopra, Sonam, Šatkauskas, Saulius   +4 more
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A comparison of calcium phosphate coprecipitation and electroporation

Molecular Biotechnology, 1998
Plasmid-based transfection assays provide a rapid means to measure homologous and nonhomologous recombination in mammalian cells. Often it is of interest to examine the stimulation of recombination by DNA damage induced by radiation, genotoxic chemicals, or nucleases. Transfection is frequently performed by using calcium phosphate coprecipitation (CPP),
J A, Nickoloff, L N, Spirio, R J, Reynolds   +2 more
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The effect of electroporation on iontophoretic transdermal delivery of calcium regulating hormones

Journal of Controlled Release, 2000
Electrically-assisted delivery by iontophoresis and/or electroporation was used in vitro to deliver the calcium regulating hormones, salmon calcitonin (sCT) and parathyroid hormone (1-34) (PTH) through human epidermis. Such delivery could be useful for chronic treatment of post-menopausal osteoporosis and other clinical indications as a superior ...
S L, Chang, G A, Hofmann, L, Zhang, L J, Deftos, A K, Banga   +4 more
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Single-Cell Electroporation for Measuring In Vivo Calcium Dynamics in Microglia

2019
Similar to many nonexcitable cells, microglia utilize intracellular Ca2+ signaling for the communication with each other as well as neurons and astrocytes and for triggering a magnitude of their executive functions. However, in vivo measurements of the intracellular Ca2+ dynamics in microglia have been challenging due to technical reasons.
Bianca, Brawek, Olga, Garaschuk
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Calcium Electroporation: An Overview of an Innovative Cancer Treatment Approach

2019 PhotonIcs & Electromagnetics Research Symposium - Spring (PIERS-Spring), 2019
Electroporation (EP) involves the application of short (ms to $\mu\mathrm{s}$ ), high voltage electric pulses to increase the permeability of biological membranes to external ions or molecules. In the clinical practice, reversible EP is used to increase the uptake of chemotherapeutic drugs in local, nonthermal tumor treatment (electrochemotherapy, ECT)
Romeo, Stefania, Frandsen, Stine Krog, Gehl, Julie, Zeni, Olga   +3 more
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Thermal Profile of Contact Force Dependent Pulse Field Electroporation Beyond Calcium Electroporation at the Koch Triangle

Pacing and Clinical Electrophysiology
ABSTRACT Background Contact force (CF)‐dependent pulse field electroporation (PFE) may generate tissue heating, affecting junctional rhythm at the triangle of Koch (ToK) in a clinical setting. PFE may also disrupt calcium homeostasis, causing calcium electroporation (CE) for some Joule heating.
Yiqi Lu, Huimin Chu, Rong Bai, Feifan Ouyang, Zhenyu Jia, Mingjun Feng, Xianfeng Du, Si Chen, Lipu Yu, Jiating Dai, Tingsha Du, Weidong Zhuo, Yijun Sun, Xinzhi Yu, Chenxu Luo, Caijie Shen   +15 more
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Investigation of cell viability regulation by calcium electroporation

2018
Electroporation is a method, developed in order to deliver exogenous biocompounds (anticancer drugs, nucleic acids, proteins, etc.) to cells and tissues, which are mostly designed for cancer treatment purposes. The synergistic effect of electroporation and chemotherapeutic agents has been widely studied for cancer cell treatment both in vitro and in ...
Navickaitė, Diana, Mažuolis, Mindaugas, Maciulevičius, Martynas, Šatkauskas, Saulius   +3 more
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Bystander effect induced by combined calcium electroporation, bleomycin electrotransfer, and irreversible electroporation

Electroporation, a technique utilizing electric fields topermeabilize cell membranes, holds promise for localized cancer treatment. Depending on the intensity and duration of the electric pulses, electroporation can be either reversible, facilitating drug delivery (e.g., electrochemotherapy with bleomycin[1]), or irreversible, leading to cell death ...
Barauskaitė-Šarkinienė, Neringa, Borinskytė, Ugnė, Ruzgys, Paulius, Šatkauskas, Saulius   +3 more
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Calcium electroporation in cancer treatment -a curriculum development

2019
Lindhardt, Christina-Louise; id_orcid 0000-0002-7476-8210, Dyrlund, Mette, Askham, Barbara, Vestergaard, Kitt, Van Halsema, Anna, Koepke, Sascha   +5 more
openaire   +2 more sources