Results 1 to 10 of about 7,712,280 (384)
Denoising two-photon calcium imaging data. [PDF]
PLoS ONE, 2011 Two-photon calcium imaging is now an important tool for in vivo imaging of biological systems. By enabling neuronal population imaging with subcellular resolution, this modality offers an approach for gaining a fundamental understanding of brain anatomy ...
Wasim Q Malik +3 more
doaj +7 more sources
F1000Research, 2021 Techniques for calcium imaging were first demonstrated in the mid-1970s, whilst tools to analyse these markers of cellular activity are still being developed and improved today.
Miranda Robbins +3 more
doaj +2 more sources
Neuronal Graphs: A Graph Theory Primer for Microscopic, Functional Networks of Neurons Recorded by Calcium Imaging [PDF]
Frontiers in Neural Circuits, 2021 Connected networks are a fundamental structure of neurobiology. Understanding these networks will help us elucidate the neural mechanisms of computation. Mathematically speaking these networks are “graphs”—structures containing objects that are connected.
Carl J. Nelson, Stephen Bonner
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A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium [PDF]
Nature Communications, 2021 Currently, genetically encoded calcium indicators are not suitable for direct quantification. Here the authors engineer a fluorescence lifetime imaging calcium biosensor, Turquoise Calcium Fluorescence LIfeTime Sensor (Tq-Ca-FLITS), and measure ...
Franka H. van der Linden +12 more
doaj +2 more sources
Inferring spikes from calcium imaging in dopamine neurons.
PLoS ONE, 2021 Calcium imaging has led to discoveries about neural correlates of behavior in subcortical neurons, including dopamine (DA) neurons. However, spike inference methods have not been tested in most populations of subcortical neurons.
Weston Fleming +4 more
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In vivo measurement of afferent activity with axon-specific calcium imaging. [PDF]
Nature Neuroscience, 2018 In vivo calcium imaging from axons provides direct interrogation of afferent neural activity, informing the neural representations that a local circuit receives.
Broussard, Gerard Joey +8 more
core +2 more sources
Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish. [PDF]
eNeuro, 2019 Seizures are characterized by hypersynchronization of neuronal networks. Understanding these networks could provide a critical window for therapeutic control of recurrent seizure activity, i.e., epilepsy.
Baraban, Scott C, Liu, Jing
core +3 more sources
Assessing spontaneous sensory neuron activity using in vivo calcium imaging
bioRxiv, 2023 Heightened spontaneous activity in sensory neurons is often reported in individuals living with chronic pain. It is possible to study this activity in rodents using electrophysiology, but these experiments require great skill and can be prone to bias ...
Sonia L Ingram +5 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2021 X-linked hypophosphatemia (XLH) is the most common form of genetic rickets. Mainly diagnosed during childhood because of growth retardation and deformities of the lower limbs, the disease affects adults with early enthesopathies and joint structural ...
Axelle Cauliez +16 more
doaj +1 more source
Nature Methods, 2021 Calcium imaging has transformed neuroscience research by providing a methodology for monitoring the activity of neural circuits with single-cell resolution.
Xinyang Li +10 more
semanticscholar +1 more source