Results 61 to 70 of about 7,712,280 (384)

Fast and robust active neuron segmentation in two-photon calcium imaging using spatiotemporal deep learning

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Two-photon calcium imaging is a standard technique of neuroscience laboratories that records neural activity from individual neurons over large populations in awake-behaving animals.
Somayyeh Soltanian-Zadeh   +4 more
semanticscholar   +1 more source

Laser induced calcium oscillations in fluorescent calcium imaging

open access: yesGeneral physiology and biophysics, 2018
Phototoxicity is the most common problem investigators may encounter when performing live cell imaging. It develops due to excess laser exposure of cells loaded with fluorophores and can lead to often overlooked but significant artifacts, such as massive increase of intracellular Ca2+ concentration, which would make data interpretation problematic ...
Vincze, János   +7 more
openaire   +4 more sources

Calcium Imaging in Neuron Cell Death [PDF]

open access: yes, 2014
Intracellular Ca2+ is involved in control of a large variety of cell functions including apoptosis and neuron cell death. For example, intracellular Ca2+ overload is critical in neuron cell death induced by excitotoxicity. Thus, single cell monitoring of intracellular Ca2+ concentration ([Ca2+]cyt ) in neurons concurrently with apoptosis and neuron ...
Calvo-Rodríguez, María   +2 more
openaire   +4 more sources

Hierarchy of neural organization in the embryonic spinal cord: Granger-causality graph analysis of in vivo calcium imaging data

open access: yes, 2014
The recent development of genetically encoded calcium indicators enables monitoring in vivo the activity of neuronal populations. Most analysis of these calcium transients relies on linear regression analysis based on the sensory stimulus applied or the ...
Chavez, Mario   +4 more
core   +3 more sources

Crystallization of calcite from amorphous calcium carbonate: earthworms show the way [PDF]

open access: yes, 2008
No abstract ...
Canti   +5 more
core   +1 more source

Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain

open access: yesbioRxiv, 2019
1300-nm three-photon calcium imaging has emerged as a useful technique to allow calcium imaging in deep brain regions. Application to large-scale neural activity imaging entails a careful balance between recording fidelity and tissue heating.
Tianyu Wang   +8 more
semanticscholar   +1 more source

Continuous volumetric imaging via an optical phase-locked ultrasound lens

open access: yes, 2016
In vivo imaging at high spatiotemporal resolution is key to the understanding of complex biological systems. We integrated an optical phase-locked ultrasound lens into a two-photon fluorescence microscope and achieved microsecond-scale axial scanning ...
Cui, M.   +7 more
core   +1 more source

Glutamate-mediated blood-brain barrier opening. implications for neuroprotection and drug delivery [PDF]

open access: yes, 2016
The blood-brain barrier is a highly selective anatomical and functional interface allowing a unique environment for neuro-glia networks. Blood-brain barrier dysfunction is common in most brain disorders and is associated with disease course and delayed ...
CECCANTI , MARCO   +18 more
core   +1 more source

Online analysis of microendoscopic 1-photon calcium imaging data streams

open access: yesbioRxiv, 2020
In-vivo calcium imaging through microendoscopic lenses enables imaging of neuronal populations deep within the brains of freely moving animals. Previously, a constrained matrix factorization approach (CNMF-E) has been suggested to extract single-neuronal
Johannes Friedrich   +2 more
semanticscholar   +1 more source

Fast and sensitive GCaMP calcium indicators for imaging neural populations

open access: yesbioRxiv, 2021
Using large-scale screening and structure-guided mutagenesis, fast and sensitive GCaMP sensors are developed and optimized with improved kinetics without compromising sensitivity or brightness.
Yan Zhang   +23 more
semanticscholar   +1 more source

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