Results 71 to 80 of about 2,798,160 (306)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Dendritic spike induction of postsynaptic cerebellar LTP [PDF]
The architecture of parallel fiber (PF) axons contacting cerebellar Purkinje neurons (PNs) retains spatial information over long distances. PF synapses can trigger local dendritic calcium spikes, but whether and how this calcium signal leads to plastic ...
Marco Canepari, Kaspar E. Vogt
core
Calcium and sulphur distribution in fired clay brick in the presence of a black reduction core using micro X-ray fluorescence mapping [PDF]
A new finding of the observation of an elemental gradient or zoning of calcium and sulphur in fired brick bodies is described, that does not appear to have been reported in the literature before.
L. Gredmaier +5 more
core +1 more source
Calcium-induced ScCdc31 droplets display surface wetting.
Transmission time lapse imaging of recombinant ScCdc31-6His protein droplets in solution at 200 μM concentration displays surface after calcium addition. 50 mM BisTris (pH 7.1), addition of CaCl2 to 2 mM, 37°C. Time lapse is 1 second per frame.
Nicolas P. Lichti (17583421) +4 more
core +1 more source
In recent years functional multiphoton (MP) imaging of vital mouse tissues and stimulation emission depletion (STED) imaging of optically cleared tissues allowed new insights into kidney biology.
Eva Wiesner +6 more
doaj +1 more source
Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis
Claudins are a family of proteins that forms paracellular barriers and pores determining tight junctions (TJ) permeability. Claudin-16 and -19 are pore forming TJ proteins allowing calcium and magnesium reabsorption in the thick ascending limb of Henle's
Claire Bardet +11 more
doaj +1 more source
Design and Initial Characterization of a Small Near-Infrared Fluorescent Calcium Indicator
Near-infrared (NIR) genetically encoded calcium indicators (GECIs) are becoming powerful tools for neuroscience. Because of their spectral characteristics, the use of NIR GECIs helps to avoid signal loss from the absorption by body pigments, light ...
Mikhail E. Matlashov +5 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Calcium-induced TbCenA droplets are fusogenic.
Transmission time lapse imaging of recombinant TbCenA-6His protein droplets in solution at 100 μM concentration displays fusion events after calcium addition. 50 mM BisTris (pH 7.1), addition of CaCl2 to 2 mM, 37°C.
Nicolas P. Lichti (17583421) +4 more
core +1 more source

