Results 61 to 70 of about 2,798,160 (306)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Calcium imaging data for 3 mice in spontaneous and task ('cr' and 'hit ...
Yasir Gallero-Salas (8604732) +1 more
core +1 more source
Calcium Imaging in Drosophila melanogaster
Drosophila melanogaster, colloquially known as the fruit fly, is one of the most commonly used model organisms in scientific research. Although the final architecture of a fly and a human differs greatly, most of the fundamental biological mechanisms and pathways controlling development and survival are conserved through evolution between the two ...
Vajente N. +3 more
openaire +2 more sources
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Calcium imaging in a FlAsH [PDF]
A new calcium indicator called Calcium Green FlAsH allows researchers to monitor rapid and localized calcium dynamics in the cell.
openaire +1 more source
Acetylcholine regulation of GnRH neuronal activity: A circuit in the medial septum
In vertebrates, gonadotropin-releasing hormone (GnRH)-secreting neurons control fertility by regulating gonadotrophs in the anterior pituitary. While it is known that acetylcholine (ACh) influences GnRH secretion, whether the effect is direct or indirect,
David M. Shostak +3 more
doaj +1 more source
Intracellular calcium imaging for agonist screening. [PDF]
Calcium ions are involved in the regulation of a wide range of physiological activities such as nerve conduction, muscle contraction, cell division and gene expression through local calcium transients and global calcium oscillations. Calcium homeostasis modulator 1 (CALHM1) is a novel plasma membrane large-pore ion channel mediating calcium influx ...
Wang H, Yang B, Mo L, Yang HQ.
europepmc +3 more sources
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Application of multiline two-photon microscopy to functional in vivo imaging [PDF]
Kurtz R, Fricke M, Kalb J, Tinnefeld P, Sauer M. Application of multiline two-photon microscopy to functional in vivo imaging. Journal of Neuroscience Methods.
Kalb, J +4 more
core +1 more source
Computational Methods for Neuron Segmentation in Two-Photon Calcium Imaging Data: A Survey
Calcium imaging has rapidly become a methodology of choice for real-time in vivo neuron analysis. Its application to large sets of data requires automated tools to annotate and segment cells, allowing scalable image segmentation under reproducible ...
Waseem Abbas, David Masip
doaj +1 more source

