Results 61 to 70 of about 2,798,160 (306)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Murine calcium imaging data

open access: yes, 2020
Calcium imaging data for 3 mice in spontaneous and task ('cr' and 'hit ...
Yasir Gallero-Salas (8604732)   +1 more
core   +1 more source

Calcium Imaging in Drosophila melanogaster

open access: yes, 2019
Drosophila melanogaster, colloquially known as the fruit fly, is one of the most commonly used model organisms in scientific research. Although the final architecture of a fly and a human differs greatly, most of the fundamental biological mechanisms and pathways controlling development and survival are conserved through evolution between the two ...
Vajente N.   +3 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Calcium imaging in a FlAsH [PDF]

open access: yesNature Methods, 2007
A new calcium indicator called Calcium Green FlAsH allows researchers to monitor rapid and localized calcium dynamics in the cell.
openaire   +1 more source

Acetylcholine regulation of GnRH neuronal activity: A circuit in the medial septum

open access: yesFrontiers in Endocrinology, 2023
In vertebrates, gonadotropin-releasing hormone (GnRH)-secreting neurons control fertility by regulating gonadotrophs in the anterior pituitary. While it is known that acetylcholine (ACh) influences GnRH secretion, whether the effect is direct or indirect,
David M. Shostak   +3 more
doaj   +1 more source

Intracellular calcium imaging for agonist screening. [PDF]

open access: yesBiophys Rep
Calcium ions are involved in the regulation of a wide range of physiological activities such as nerve conduction, muscle contraction, cell division and gene expression through local calcium transients and global calcium oscillations. Calcium homeostasis modulator 1 (CALHM1) is a novel plasma membrane large-pore ion channel mediating calcium influx ...
Wang H, Yang B, Mo L, Yang HQ.
europepmc   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Application of multiline two-photon microscopy to functional in vivo imaging [PDF]

open access: yes, 2006
Kurtz R, Fricke M, Kalb J, Tinnefeld P, Sauer M. Application of multiline two-photon microscopy to functional in vivo imaging. Journal of Neuroscience Methods.
Kalb, J   +4 more
core   +1 more source

Computational Methods for Neuron Segmentation in Two-Photon Calcium Imaging Data: A Survey

open access: yesApplied Sciences, 2022
Calcium imaging has rapidly become a methodology of choice for real-time in vivo neuron analysis. Its application to large sets of data requires automated tools to annotate and segment cells, allowing scalable image segmentation under reproducible ...
Waseem Abbas, David Masip
doaj   +1 more source

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