Results 91 to 100 of about 1,096,111 (252)

Mast Cells Selectively Deliver Extracellular Vesicle‐Encapsulated mRNA to Colorectal Cancer Cells

Immunology &Cell Biology, EarlyView.
Schematic overview of mast cell‐colorectal cancer cell interactions. Mast cells bind to colorectal cancer cells through integrin‐mediated adhesion (1). Calcium influx arises in mast cells (2). Calcium signaling is required for the release of mRNA‐ and protein‐containing vesicles (3), resulting in the transfer of mast cell‐derived mRNA and proteins to ...
Rosie Lanzloth, Bader El Farran, Ram Podicheti, Douglas B. Rusch, Heather M. O'Hagan   +4 more
wiley   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, EarlyView.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source

Calcium ionophore A-23187 inhibits the secretion of β-hexosaminidase from the GG2EE mouse macrophage cell line [PDF]

, 1992
Secretion of the lysosomal enzyme β-N-acetylhexosaminidase is inhibited by calcium ionophore A-23187 in the GG2EE macrophage cell line. Such inhibition is time and dose dependent.
DATTI, Alessandro, FARINELLI, Senia, BLASI E., BECCARI, Tommaso, ORLACCHIO, Aldo   +4 more
core   +2 more sources

In Vitro Capacitation in Boar Sperm: Evaluation of Selected Detection Techniques

Methods and Protocols
Sperm capacitation is essential for fertilization and involves coordinated changes in membrane organization, ion fluxes, and intracellular signaling. However, commonly used detection methods may reflect different biological events, which can be strongly ...
Barbora Klusackova, Zuzana Pilsova, Katerina Nemeckova, Aneta Pilsova, Pavla Postlerova   +4 more
doaj   +1 more source

Effects of Panax ginseng, zearalenol, and estradiol on sperm function

Journal of Ginseng Research, 2016
Background: Estrogen signaling pathways are modulated by exogenous factors. Panax ginseng exerts multiple activities in biological systems and is classified as an adaptogen.
Sandra L. Gray, Brett R. Lackey, William R. Boone   +2 more
doaj   +1 more source

Metabolic stimulation improves bioenergetics and haematologic indices of circulating erythrocytes from sickle cell mice

The Journal of Physiology, EarlyView.
Abstract figure legend Metabolic stimulation improves bioenergetics, redox state, hydration and hematologic indices of circulating erythrocytes from sickle cell mice. Retained mitochondria in circulating RBCs from sickle mice are a source of RBC ATP as mitochondria function (ETC, electron transport chain) inhibitors [rotenone, a mitochondrial complex I
Luis E. F. Almeida, Meghann L. Smith, Sayuri Kamimura, Sebastian Vogel, Zenaide M. N. Quezado   +4 more
wiley   +1 more source

A study of calcium carbonate formation in biological systems [PDF]

, 1983
This thesis has studied aspects of biomineralisation, covering the inorganic mineral, the organic matrix, the possible use of phospholipid bilayer vesicles to control mineralisation, calcium and other metal binding to an antibiotic ionophore, Lasalocid-A
Parker, Stephen Barry, Parker, Stephen Barry.   +1 more
core   +2 more sources

Engineered Red Blood Cell‐Derived Extracellular Vesicles With Klotho Peptide Protect the Kidney From Fibrosis

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
In this study, we engineered red blood cell–derived extracellular vesicles with a Klotho‐derived peptide (RBC‐EVKP1) to target kidney fibrosis. Engineered RBC‐EVKP1, through inhibition of TGF‐β2/TGFβ receptor binding, and downstream signaling, reduced fibrotic and mesenchymal marker expression and extracellular matrix accumulation in proximal tubular ...
Tunahan Ergunay, Alessia Brossa, Michela Arena, Stefania Bruno, Alessandro Gori, Anne Metje van Genderen, Rosalinde Masereeuw, Benedetta Bussolati   +7 more
wiley   +1 more source

Priming of neutrophils and macrophages for enhanced release of superoxide anion by the calcium ionophore ionomycin. Implications for regulation of the respiratory burst.

Journal of Biological Chemistry, 1987
Phagocytic cells can be primed for enhanced stimulated release of superoxide anion (O2-) by exposure to a variety of biologic agents, including gamma-interferon and lipopolysaccharide.
T. Finkel, M. Pabst, H. Suzuki, L. Guthrie, J. Forehand, W. Phillips, R. Johnston   +6 more
semanticscholar   +1 more source

The Multifaceted Role of Pyroptosis: Molecular Mechanisms, Crosstalk with Other Cell Death Pathways, and Therapeutic Implications

MedComm, Volume 7, Issue 7, July 2026.
Pyroptosis maintains immune homeostasis by eliminating damaged or infected cells, but its dysregulation promotes inflammation and cancer progression. The diagram illustrates key activation pathways, links with other programmed cell deaths, and cancer‐specific effects, enhancing its dual protective and pathogenic roles.
Diego Liviu Boaru, Patricia De Castro‐Martinez, Cielo Garcia‐Montero, Oscar Fraile‐Martinez, Majd N. Michael Alhaddadin, Silvestra Barrena‐Blázquez, Laura Lopez‐Gonzalez, Clara Tasende Fernández, Ricardo Alvarado‐Hurtado, Tomás Ratia Giménez, Inmaculada Lasa‐Unzúe, Manuel Díez Alonso, Alberto Gutiérrez‐Calvo, Miguel A. Saez, David Cobo‐Prieto, Jose V. Saz, Melchor Alvarez‐Mon, Raul Diaz‐Pedrero, Miguel A. Ortega   +18 more
wiley   +1 more source