Results 71 to 80 of about 40,341 (222)
A cyclic effect of cAMP and calcium signaling contributes to jujube growth and development
Journal of Integrative Agriculture, 2023 3′,5′-Cyclic adenosine monophosphate (cAMP) is an important metabolite that is specifically enriched in jujube. However, the effect of cAMP on jujube cellular responses has not been comprehensively studied.
Li-xin WANG +14 more
doaj +1 more source
CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]
, 2009 The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Ackermann, Frauke +5 more
core +1 more source
Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
Journal of Applied Toxicology, EarlyView.ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source
Mediators of Inflammation, 1993 The present investigation characterizes calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis in the rat. Intraperitoneal injection of A-23187 (20 μg/rat) stimulated marked biosynthesis of 6-keto-PGF1α (6-KPA), TxB2, LTC4 and LTB4, with ...
T. S. Rao +3 more
doaj +1 more source
The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li +4 more
wiley +1 more source
Asian Pacific Journal of ReproductionRationale: This case report describes a couple with recurrent fertilization failure despite undergoing multiple cycles of intracytoplasmic sperm injection (ICSI).
Akash More +4 more
doaj +1 more source
Flow Cytometric Analysis of Calcium Influx Assay in T cells
Bio-Protocol, 2013 Calcium influx is one of the key signaling events upon stimulation of T cell receptors (TCR) and plays an important role for T cell activation, proliferation, and differentiation.
Sun-Hwa Lee
doaj +1 more source
Usnic acid as calcium ionophore and mast cells stimulator
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2020 Usnic acid (UA), a secondary lichen metabolite, has long been popular as one of natural fat-burning dietary supplements. Similar to 2,4-dinitrophenol, the weight-loss effect of UA is assumed to be associated with its protonophoric uncoupling activity.
Maria A, Chelombitko +7 more
openaire +2 more sources
A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals
British Journal of Pharmacology, EarlyView.Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig +7 more
wiley +1 more source
The Effect of Calcium Ionophores on Fragmented Sarcoplasmic Reticulum [PDF]
The Journal of General Physiology, 1972 X-537 A and A 23187, two antibiotics which form liphophilic complexes with divalent cations, function as ionophores in vesicular fragments of sarcoplasmic reticulum (SR). Addition of either ionophore to SR preloaded with calcium in the presence of adenosine triphosphate (ATP), causes rapid release of calcium. Furthermore, net calcium accumulation by SR
A, Scarpa, J, Baldassare, G, Inesi
openaire +2 more sources