Results 81 to 90 of about 1,096,111 (252)
Immunomodulatory and Cytotoxic Properties of Enniatin B1 in Porcine Alveolar Macrophages
Journal of Applied Toxicology, EarlyView.ABSTRACT This study investigates the immunomodulatory effects of Enniatin B1 (ENNB1), an emerging mycotoxin, on porcine alveolar macrophages (PAMs), a species‐specific model relevant to human innate immunity. PAMs were exposed to increasing ENNB1 concentrations (0.5–6 μM) over 6, 24, and 48 h.
Sara Frazzini +4 more
wiley +1 more source
Pest Management Science, EarlyView.Two virulence strategies in Beauveria: a growth strategy characterized by rapid within‐host proliferation, and a toxin strategy involving antimicrobial activity and toxicity to insects Abstract BACKGROUND Pathogen virulence is often attributed to toxin production, yet toxins are metabolically costly and may not universally enhance fitness.
Shasha Hu +3 more
wiley +1 more source
Journal of Biological Chemistry, 1989 It has recently been demonstrated that the chemotactic peptide N-formyl-Met-Leu-Phe activates phospholipase D (PLD) in dimethyl sulfoxide-differentiated HL-60 granulocytes to produce phosphatidic acid (PA) and, in the presence of ethanol ...
M. Billah +4 more
semanticscholar +1 more source
Small, EarlyView.SAFE (Sonication‐Assisted liposome Fusion with EVs) is a rapid, mix‐and‐read assay that directly detects extracellular vesicle–encapsulated miRNAs from unprocessed plasma. By delivering molecular beacons into EVs via sonication‐driven liposome fusion, the method enables intravesicular hybridization with minimal background, providing quantitative ...
Subhra Sulipta Jena +9 more
wiley +1 more source
Effect of calcium ions on the aggregation of highly phosphorylated tau
Biochemistry and Biophysics ReportsTau is typically an axonal protein, but in neurons of brains affected by Alzheimer's disease (AD), aggregation of hyperphosphorylated tau in the somatodendritic compartment causes neuronal death.
Toru Tanaka +3 more
doaj +1 more source
Molecules, 2014 This study aimed to evaluate the anti-allergic potential of Echium plantagineum L. bee pollen and to characterize its primary metabolites. The activity of E.
Eduarda Moita +6 more
doaj +1 more source
A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals
British Journal of Pharmacology, EarlyView.Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig +7 more
wiley +1 more source
PLoS Pathogens, 2012 Egress from the host cell is a crucial and highly regulated step in the biology of the obligate intracellular parasite, Toxoplasma gondii. Active egress depends on calcium fluxes and appears to be a crucial step in escaping the attack from the immune ...
Erin Garrison +8 more
doaj +1 more source
GCN2 in proteostasis: structural logic, signalling networks and disease
The FEBS Journal, EarlyView.Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley +1 more source
Effect of calcium ionophore on unfertilized oocytes after ICSI cycles [PDF]
, 2013 Background: Fertilization failure is one of the most problems in assisted reproduction technology (ART). Objective: The aim of this study was the evaluation of oocytes activation by addition of calcium ionophore in unfertilized oocytes in ICSI cycles ...
Yousefnejad, Fariba +4 more
core +1 more source