Results 91 to 100 of about 2,340,161 (352)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Medication for bone loss in female patients with anorexia nervosa: a systematic review and management algorithm

Eating and Weight Disorders
Purpose Anorexia Nervosa can have a major impact on bone health through low bone mass and bone loss. Considering the lack of consensual guidelines for the prevention and treatment of bone loss in this condition, a systematic review was performed to ...
Alexandra Loisel, Anne Li, Karine Briot, Marie-Rose Moro, Chantal Stheneur, Corinne Blanchet   +5 more
doaj   +1 more source

Effect of modified compound calcium phosphate cement on the differentiation and osteogenesis of bone mesenchymal stem cells

Journal of Orthopaedic Surgery and Research, 2017
Background The aim of this study is to evaluate the effect of self-invented compound calcium phosphate cement upon the proliferation and osteogenesis of bone mesenchymal stem cells (BMSCs).
Jican Zeng, Jiazhong Lin, Guanfeng Yao, Kangmei Kong, Xinjia Wang   +4 more
doaj   +1 more source

Composite material comprising pectin and calcium phosphate and method for its realisation [PDF]

, 2015
A method for obtaining a composite material including an aqueous solution of pectin and a suspension/solution of calcium phosphate mixed together, wherein said solution of pectin cross-links with a portion of the calcium obtained from the solution of ...
Bianchi, G., GIULIANO, LILIANA, MUNARIN, FABIOLA, PETRINI, PAOLA, Robotti, P., TANZI, MARIA CRISTINA   +5 more
core  

Clinical application of ceramics in anterior cervical discectomy and fusion: A review and update [PDF]

, 2017
Study Design: Narrative review. Objectives: Anterior cervical discectomy and fusion (ACDF) is a reliable procedure, commonly used for cervical degenerative disc disease. For interbody fusions, autograft was the gold standard for decades; however, limited
Abedi, Aidin, Bonaki, Hirbod, Jazayeri, Seyed B., Rahimi-Movaghar, Vafa, Vaccaro, Alex R., Zadegan, Shayan A.   +5 more
core   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Adsorption and release of BMP-2 on nanocrystalline apatite-coated and uncoated hydroxyapatite/b-tricalcium phosphate porous ceramics [PDF]

, 2009
The association of bone morphogenetic proteins (BMPs) with calcium phosphate bioceramics is known to confer them osteoinductive properties. The aim of this study was to evaluate the surface properties, especially regarding recombinant human BMP-2 (rhBMP-
Alam, Baig, Barroug, Barroug, Benaziz, Bohic, Boix, Charlot, Coradin, Daculsi, Dong, Frolik, Habibovic, Habibovic, Hayakawa, Hughes Wassell, Klenke, Le Nihouannen, Liu, Liu, Matsumoto, Midy, Midy, Murata, Ouizat, Rey, Rey, Rey, Rouahi, Ruppert, Scheufler, Schmoekel, Seeherman, Sumner, Tsujigiwa, Uludag, Vehof, Yuan, Zisch   +38 more
core   +3 more sources

Collagen-calcium phosphate composites

Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 1998
There is a widespread clinical need for bone augmentation and replacement. The major solid phases of bone are collagen and calcium phosphate and a bone analogue based on these two constituents should have some useful properties. In this review this theme is developed and the properties of natural and naturally based composites are compared. Composites
Lawson, A, Czernuszka, J
openaire   +3 more sources

Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

Nature Communications, 2019
Extracellular phosphate regulates its own renal excretion by eliciting concentration-dependent secretion of parathyroid hormone (PTH). However, the phosphate-sensing mechanism remains unknown and requires elucidation for understanding the aetiology of ...
Patricia P. Centeno, A. Herberger, Hee‐chang Mun, C. Tu, E. Nemeth, Wenhan Chang, A. Conigrave, D. Ward   +7 more
semanticscholar   +1 more source