Results 31 to 40 of about 23,328 (212)

Pseudogout Diagnosed By Point-of-care Ultrasound

Clinical Practice and Cases in Emergency Medicine, 2019
A 71-year-old male presented to the emergency department (ED) for worsening right knee pain for the prior 3–4 weeks. Point-of-care ultrasound (POCUS) of the right knee showed a pseudo-double contour sign.
Anthony J. Halupa, Robert J. Strony, David H. Bulbin, Chadd K. Kraus   +3 more
doaj   +1 more source

Bone without borders – Monetite-based calcium phosphate guides bone formation beyond the skeletal envelope

Bioactive Materials, 2023
Calcium phosphates (CaP) represent an important class of osteoconductive and osteoinductive biomaterials. As proof-of-concept, we show how a multi-component CaP formulation (monetite, beta-tricalcium phosphate, and calcium pyrophosphate) guides ...
Furqan A. Shah, Martina Jolic, Chiara Micheletti, Omar Omar, Birgitta Norlindh, Lena Emanuelsson, Håkan Engqvist, Thomas Engstrand, Anders Palmquist, Peter Thomsen   +9 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Formation of calcium pyrophosphate crystals in vitro: implications for calcium pyrophosphate crystal deposition disease (pseudogout) [PDF]

Annals of the Rheumatic Diseases, 1980
Little is known about how calcium pyrophosphate dihydrate (CaPPD) crystals form in vivo and give rise to chondrocalcinosis or pseudogout (pyrophosphate arthropathy or calcium pyrophosphate crystal deposition disease). In this study a simple method has been devised to define the conditions necessary for the deposition of crystals in vitro.
P R, Hearn, R G, Russell
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Chondrogenesis in the synovial tissue is associated with the onset of pseudogout after total knee arthroplasty

Arthroplasty Today, 2016
Postoperative pseudogout after total knee arthroplasty (TKA) is very rare, and its physical findings are very similar to infectious symptoms. In pseudogout, the mechanism underlying the deposition of calcium pyrophosphate dehydrate crystals remains ...
Ryosuke Sato, MD, Shunji Nakano, MD, PhD, Tomoya Takasago, MD, Masaru Nakamura, MD, Masahiro Kashima, MD, Takashi Chikawa, MD, PhD, Daisuke Hamada, MD, PhD, Tomohiro Goto, MD, PhD, Koichi Sairyo, MD, PhD   +8 more
doaj   +1 more source

Calcium Pyrophosphate Deposition Disease of the Temporomandibular Joint [PDF]

Skull Base Reports, 2011
Calcium pyrophosphate dihydrate deposition disease (CPDD, tophaceous pseudogout) is a rare crystal arthropathy characterized by calcium pyrophosphate crystal deposition in joint spaces, episodes of synovitis, and radiological features of chondrocalcinosis. We present a case of 61-year-old woman who presented with left temporomandibular joint (TMJ) pain,
Vasisht Srinivasan, Andrew Wensel, Paul Dutcher, Shawn Newlands, Mahlon Johnson, George Edward Vates   +5 more
openaire   +4 more sources

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Tuberculosis of the Wrist Accompanied with Calcium Pyrophosphate

Internal Medicine, 2017
This is a rare case of tuberculosis (TB) complicated with pseudogout of the wrist joint in a non-immunocompromised 84-year-old female with a history of pulmonary tuberculosis. She was diagnosed with extrapulmonary tuberculosis of the wrist based on a polymerase chain reaction (PCR) study and synovial fluid aspiration in which the cytology was positive ...
Watanabe, Kenya, Yamazaki, Yoshitaka, Sugawara, Mariko   +2 more
openaire   +3 more sources