Results 41 to 50 of about 22,997 (192)

A phenomap of TTR amyloidosis to aid diagnostic screening

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos   +4 more
wiley   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

open access: yesEpilepsia, EarlyView.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer   +12 more
wiley   +1 more source

Revolutionizing Healthcare With Paper‐Based Nucleic Acid Testing

open access: yesExploration, EarlyView.
This work summarizes strategies to enhance paper‐based devices for nucleic acid testing. Key approaches include optimizing paper platforms, improving nucleic acid amplification, and refining labeling/signaling methods. These advancements aim to boost sensitivity, speed, and usability, making paper‐based diagnostics more effective for point‐of‐care ...
Hong Zhang   +8 more
wiley   +1 more source

Calcium pyrophosphate crystal deposition

open access: yesInternational Journal of Clinical Rheumatology, 2011
Even though frequently asymptomatic, for some patients calcium pyrophosphate crystal deposition remains a troublesome disorder; these patients can present with recurrent episodes of painful monoarthritis, with persistent polyarticular inflammation or with mechanical joint pain and osteoarthritic changes.
Francisca Sivera   +2 more
openaire   +1 more source

Pseudogout and Calcium Pyrophosphate Disease [PDF]

open access: yesJournal of Education and Teaching in Emergency Medicine, 2017
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openaire   +4 more sources

Biomimetic mineralization‐inspired formulation‐adjuvant integrated circRNA nanovaccine against COVID‐19

open access: yesInterdisciplinary Medicine, EarlyView.
Inspired by the role of Mg2+ in stabilizing RNA secondary structures, we developed a one‐pot biomimetic mineralization method for synthesizing a circular RNA‐based nanovaccine (circRNA@FAiNVac) that integrates formulation and adjuvant functions. This nanovaccine exhibits potent immunostimulatory activation enabling multimodal immune responses and ...
Liangru Lin   +10 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

open access: yesJournal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini   +3 more
wiley   +1 more source

Nitrogen Fertilization Temporarily Enhances Phosphatase Activity in a High‐P Loamy Sand

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background Efficient plant utilization of soil phosphorus (P) is essential to reduce dependence on mineral P fertilizers in intensive agriculture. Input of mineral nitrogen (N) fertilizers and its chemical form may influence the activity of P mineralizing enzymes, but how this interaction operates under field conditions in a soil with high P ...
Ingeborg F. Pedersen   +3 more
wiley   +1 more source

Separation of trichothecene mycotoxins in a matrix of hemp (Cannabis sativa L.) seed, and quantification of deoxynivalenol in hemp grain infected with Fusarium graminearum

open access: yesJSFA reports, EarlyView.
Abstract Background Fusarium graminearum, one of the causal agents of ear rot in maize and head blight of cereal grains, also infects hemp (Cannabis sativa L. containing a maximum of 0.3% tetrahydrocannabinol or THC). This fungal pathogen produces trichothecene mycotoxins when it infects maize and cereal grains, but little is known about its production
Isabelle A. Kagan   +5 more
wiley   +1 more source

Plasma and Synovial Fluid VEGF‐A and Neuropilin‐1 in Knee Osteoarthritis: Associations With Radiographic Severity, Pain Sensitization‐Related Features, and Disease Burden

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to investigate associations of plasma and synovial fluid vascular endothelial growth factor A (VEGF‐A) and neuropilin‐1 (NRP1) levels with radiographic severity, pain sensitization‐related features, and disease burden in knee osteoarthritis (KOA). Plasma VEGF‐A and NRP1 were measured by sandwich ELISA in 120 patients with KOA (
Cheng‐Ju Tan
wiley   +1 more source

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