Results 101 to 110 of about 2,982,557 (298)
Presynaptic calcium signalling in cerebellar mossy fibres
Frontiers in Neural Circuits, 2010 Whole-cell recordings were obtained from mossy fibre terminals in adult turtles in order to characterize the basic membrane properties. Calcium imaging of presynaptic calcium signals was carried out in order to analyse calcium dynamics and presynaptic ...
Louiza B Thomsen +2 more
doaj +1 more source
Two classes of visual motion sensitive interneurons differ in direction and velocity dependency of in vivo calcium dynamics [PDF]
, 2001 Dürr V, Kurtz R, Egelhaaf M. Two classes of visual motion sensitive interneurons differ in direction and velocity dependency of in vivo calcium dynamics. Journal of neurobiology. 2001;46(4):289-300.Neurons exploit both membrane biophysics and biochemical
Egelhaaf, Martin ; https://orcid.org/ +2 more
core +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]
, 2010 Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Diane Bahuaud +13 more
core +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Editorial: The role of calcium channels in human health and disease—Volume II
Frontiers in Molecular Biosciences, 2023 Peng Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Revisiting volatile organic compounds’ role in plant communication using real-time bioimaging
Frontiers in Plant SciencePlants release Volatile Organic Compounds (VOCs) in response to insect attacks. VOC facilitates communication with neighboring, undamaged plants. In response to VOC from insect damaged plants, neighboring undamaged plants upregulate their own defenses as
Natsuko Kinoshita +3 more
doaj +1 more source
A signal processing analysis of Purkinje cells in vitro
Frontiers in Neural Circuits, 2010 Cerebellar Purkinje cells in vitro fire recurrent sequences of Sodium and Calcium spikes. Here, we analyze the Purkinje cell using harmonic analysis, and our experiments reveal that its output signal is comprised of three distinct frequency bands, which ...
Ze'ev R Abrams +5 more
doaj +1 more source