Results 181 to 190 of about 2,982,557 (298)

Multi-Omics Analysis of the Potential Mechanisms of Skin Albinism in Edangered <i>Percocypris pingi</i>: Abnormal Ubiquitination and Calcium Signal Inhibition. [PDF]

Cells
Liu S, Wu X, Zou Q, Lai J, Ni L, Deng Y, Feng Y, Song M, Li P, Du J, Li Q, Liu Y.   +11 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Specific Calcium Signal Responses in Human Keloid-Derived Fibroblasts During Cyclical Stretching: Basic Research. [PDF]

Health Sci Rep
Mineda K, Sato K, Nakahara T, Minami K, Ikushima K, Mizuguchi M, Mima S, Yamasaki H, Nagasaka S, Yamashita Y, Abe Y, Hashimoto I.   +11 more
europepmc   +1 more source

Orai, STIM, and PMCA contribute to reduced calcium signal generation in CD8⁺ T cells of elderly mice. [PDF]

Aging (Albany NY), 2020
Angenendt A, Steiner R, Knörck A, Schwär G, Konrad M, Krause E, Lis A.   +6 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Study on Synergistic Treatment of Pancreatic Cancer by Multiple Small Interfering Ribonucleic Acid Lipid Nanoparticles of Disk Domain Receptor 1, Transforming Growth Factor β1, Tumor-Associated Calcium Signal Transduction Protein 2, and Polyligand Proteoglycan 1. [PDF]

Pharmaceutics
Wang R, Zeng Y, Zeng Z, Xie T.
europepmc   +1 more source

Calcium time course as a signal for spike–timing–synaptic–plasticity

, 2005
Carson C. Chow.
Carson C. Chow, Richard C. Gerkin, Guo-qiang Bi, Jonathan E, Jonathan E. Rubin   +4 more
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Calcium Signal Analysis in the Zebrafish Heart via Phase Matching of the Cardiac Cycle. [PDF]

Bio Protoc
Zhang RJ, Vermot J, Gherardi R, Fukui H, Chow RW.   +4 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source