Results 241 to 250 of about 777,357 (346)

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Calcium signaling in postsynaptic mitochondria: mechanisms, dynamics, and role in ATP production. [PDF]

Front Mol Neurosci
Feofilaktova T, Kushnireva L, Segal M, Korkotian E.   +3 more
europepmc   +1 more source

Role of melatonin on calcium signaling and mitochondrial oxidativestress in epilepsy: focus on TRP channels

, 2015
Mustafa Nazıroğlu
openalex   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Dysregulated calcium signaling in the aged primate association cortices: vulnerability to Alzheimer's disease neuropathology. [PDF]

Front Aging Neurosci
Arnsten AFT, Perone I, Wang M, Yang S, Uchendu S, Bolat D, Datta D.   +6 more
europepmc   +1 more source

DNA CIRCULOMICS IN MURINE DNASE KNOCKOUT MODELS OF SLE REVEALS ENRICHMENT OF CALCIUM SIGNALING PATHWAYS IN LIVER [PDF]

Daniela Gerovska, Alexandra Kretz, Marcos J. Araúzo‐Bravo   +2 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Pathological Calcium Signaling in Traumatic Brain Injury and Alzheimer's Disease: From Acute Neuronal Injury to Chronic Neurodegeneration. [PDF]

Int J Mol Sci
Neuschmid S, Schallerer C, Ehrlich BE, McGuone D.   +3 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Correction to "Magnetite Nanodiscs Activate Mechanotransductive Calcium Signaling in Diverse Cell Types". [PDF]

J Am Chem Soc
Beckham JL, Kim YJ, Vargas Paniagua E, Kent N, Nagao K, Selvaraji S, Koehler F, Malkin E, Smith X, Tabet A, Kang S, Anikeeva P.   +11 more
europepmc   +1 more source