Results 261 to 270 of about 1,856,966 (308)
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Calcium signalling in diabetes
Cell Calcium, 2014Molecular cascades responsible for Ca(2+) homeostasis and Ca(2+) signalling could be assembled in highly plastic toolkits that define physiological adaptation of cells to the environment and which are intimately involved in all types of cellular pathology. Control over Ca(2+) concentration in different cellular compartments is intimately linked to cell
Guerrero-Hernandez, A +1 more
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Calcium signalling in oligodendrocytes
Neurophysiology, 1995Generation of calcium signal in mammalian oligodendrocytes is a result of two different mechanisms, namely: (i) transmembrane calcium influx via voltage-operated calcium channels, and (ii) calcium release from IP3-sensitive internal calcium stores.
Verkhratsky, A; id_orcid 0000-0003-2592-9898 +2 more
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Cellular and Molecular Life Sciences, 2000
The topic of nuclear Ca2+ signalling is beset by discrepant observations of substantial nuclear/cytoplasmic gradients. The reasons why some labs have recorded such gradients, whilst other workers see equilibration of Ca2+(cyt) and Ca2+(nuc) using the same cells and techniques, is unexplained.
M D, Bootman +4 more
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The topic of nuclear Ca2+ signalling is beset by discrepant observations of substantial nuclear/cytoplasmic gradients. The reasons why some labs have recorded such gradients, whilst other workers see equilibration of Ca2+(cyt) and Ca2+(nuc) using the same cells and techniques, is unexplained.
M D, Bootman +4 more
openaire +2 more sources
Calcium signaling at fertilization
Current Biology, 1992Calcium is well established as a second messenger in a diverse array of cell activities. Changes in intracellular Ca2+ activities range from localized releases to complex oscillations, which may encode specific cellular signals. The full variety of calcium responses is observed during the fertilization of different animal oocytes and eggs.
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Calcium and signal transduction
Biochemistry and Molecular Biology Education, 2008AbstractCell signaling is an essential process in which a variety of external signals, defined as first messengers, are translated inside the cells into specific responses, which are mediated by a less numerous group of second messengers. The exchange of signals became a necessity when the transition from monocellular to pluricellular life brought with
Fedrizzi, Laura +2 more
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The Language of Calcium Signaling
Annual Review of Plant Biology, 2010Ca2+ signals are a core regulator of plant cell physiology and cellular responses to the environment. The channels, pumps, and carriers that underlie Ca2+ homeostasis provide the mechanistic basis for generation of Ca2+ signals by regulating movement of Ca2+ ions between subcellular compartments and between the cell and its extracellular environment ...
Dodd, Antony N. +2 more
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Calcium signalling in lymphocytes
Current Opinion in Immunology, 2003The modulation of intracellular calcium ion concentration, [Ca(2+)](i), is a common signalling mechanism used in many biological systems. B and T lymphocytes rely on Ca(2+) signalling to initiate both developmental and activation programs. Recent data has shed new light on the initiation of this signalling pathway, the connection between the release of
Monte M, Winslow +2 more
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Calcium signaling and epilepsy
Cell and Tissue Research, 2014Calcium signaling is involved in a multitude of physiological and pathophysiological mechanisms. Over the last decade, it has been increasingly recognized as an important factor in epileptogenesis, and it is becoming obvious that the excess synchronization of neurons that is characteristic for seizures can be linked to various calcium signaling ...
Ortrud Steinlein
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Cell Calcium, 2005
In hepatocytes, hormones linked to the formation of the second messenger inositol 1,4,5-trisphosphate (InsP3) evoke transient increases or spikes in cytosolic free calcium ([Ca2+]i), that increase in frequency with the agonist concentration. These oscillatory Ca2+ signals are thought to transmit the information encoded in the extracellular stimulus to ...
Lawrence D, Gaspers, Andrew P, Thomas
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In hepatocytes, hormones linked to the formation of the second messenger inositol 1,4,5-trisphosphate (InsP3) evoke transient increases or spikes in cytosolic free calcium ([Ca2+]i), that increase in frequency with the agonist concentration. These oscillatory Ca2+ signals are thought to transmit the information encoded in the extracellular stimulus to ...
Lawrence D, Gaspers, Andrew P, Thomas
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Mechanosensory Calcium Signaling
2012Mechanotransduction describes the cellular process by which mechanical stimuli are translated into intracellular adaptive responses through biochemical signals. Current research has begun to focus on the once-forgotten organelle, the primary cilia, in this mechanotransduction process. Primary cilia are found on almost every cell type, with a functional
Thomas J, Jones, Surya M, Nauli
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