Results 271 to 280 of about 518,632 (310)
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Calcium Signalling in the Endothelium
2006Elevations in cytosolic Ca2+ concentration are the usual initial response of endothelial cells to hormonal and chemical transmitters and to changes in physical parameters, and many endothelial functions are dependent upon changes in Ca2+ signals produced.
Q K, Tran, H, Watanabe
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Calcium and signal transduction
Biochemistry and Molecular Biology Education, 2008AbstractCell signaling is an essential process in which a variety of external signals, defined as first messengers, are translated inside the cells into specific responses, which are mediated by a less numerous group of second messengers. The exchange of signals became a necessity when the transition from monocellular to pluricellular life brought with
Fedrizzi, Laura +2 more
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The Language of Calcium Signaling
Annual Review of Plant Biology, 2010Ca2+ signals are a core regulator of plant cell physiology and cellular responses to the environment. The channels, pumps, and carriers that underlie Ca2+ homeostasis provide the mechanistic basis for generation of Ca2+ signals by regulating movement of Ca2+ ions between subcellular compartments and between the cell and its extracellular environment ...
Dodd, Antony N. +2 more
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Mechanosensory Calcium Signaling
2012Mechanotransduction describes the cellular process by which mechanical stimuli are translated into intracellular adaptive responses through biochemical signals. Current research has begun to focus on the once-forgotten organelle, the primary cilia, in this mechanotransduction process. Primary cilia are found on almost every cell type, with a functional
Thomas J, Jones, Surya M, Nauli
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Calcium signaling in neuroglia
2021Glial cells exploit calcium (Ca2+) signals to perceive the information about the activity of the nervous tissue and the tissue environment to translate this information into an array of homeostatic, signaling and defensive reactions. Astrocytes, the best studied glial cells, use several Ca2+ signaling generation pathways that include Ca2+ entry through
Lim D. +3 more
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Trends in Neurosciences, 1988
very cell in an organism has a specialized task or function. As investigators, we are constantly posing the questions 'How is this function carried out? How is it regulated?' It is now a fundamental tenet of modem biology that small diffusible second messen- ger molecules act within the cell to provide a link between stimulus and output.
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very cell in an organism has a specialized task or function. As investigators, we are constantly posing the questions 'How is this function carried out? How is it regulated?' It is now a fundamental tenet of modem biology that small diffusible second messen- ger molecules act within the cell to provide a link between stimulus and output.
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Calcium Signaling in the Liver
Comprehensive Physiology, 2013Abstract Intracellular free Ca 2+ ([Ca 2+ ]i) is a highly versatile second messenger that regulates a wide range of functions in every type of cell and tissue. To achieve this versatility, the Ca 2+
Maria Jimena, Amaya +1 more
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Calcium signalling in diabetes
Cell Calcium, 2014Molecular cascades responsible for Ca(2+) homeostasis and Ca(2+) signalling could be assembled in highly plastic toolkits that define physiological adaptation of cells to the environment and which are intimately involved in all types of cellular pathology. Control over Ca(2+) concentration in different cellular compartments is intimately linked to cell
Guerrero-Hernandez, A +1 more
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Calcium signalling in oligodendrocytes
Neurophysiology, 1995Generation of calcium signal in mammalian oligodendrocytes is a result of two different mechanisms, namely: (i) transmembrane calcium influx via voltage-operated calcium channels, and (ii) calcium release from IP3-sensitive internal calcium stores.
Verkhratsky, A; id_orcid 0000-0003-2592-9898 +2 more
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Calcium signaling and apoptosis
Biochemical and Biophysical Research Communications, 2003Ca(2+) is one of the key regulators of cell survival, but Ca(2+) can also induce apoptosis in response to a variety of pathological conditions. The pro-apoptotic effects of Ca(2+) are mediated by a diverse range of Ca(2+)-sensitive factors that are compartmentalized in various intracellular organelles including the ER, cytoplasm, and mitochondria.
György, Hajnóczky +2 more
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