Results 251 to 260 of about 6,202,090 (405)

Dysregulation of STS in keratinocytes promotes calcium signaling and differentiation. [PDF]

Sci Rep
Kwon TU, Kwon YJ, Park H, Kang YJ, Chun YJ.   +4 more
europepmc   +1 more source

Optical recording of light-evoked calcium signals in the functionally intact retina

, 1999
Winfried Denk, Peter B. Detwiler
openalex   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

Molecular Oncology, Volume 19, Issue 5, Page 1452-1470, May 2025.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti, Shingo Inagaki, Tuyen Thuy Bich Ho, Akihiro Seki, Keiko Yoshida, Kosuke Satomura, Yoshio Sakai, Shuichi Kaneko, Taro Yamashita   +8 more
wiley   +1 more source

Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation. [PDF]

Front Aging Neurosci
Bathla S, Datta D, Bolat D, Woo E, Duque A, Arellano JI, Arnsten AFT, Nairn AC.   +7 more
europepmc   +1 more source

Calexcitin: A signaling protein that binds calcium and GTP, inhibits potassium channels, and enhances membrane excitability

, 1996
Thomas J. Nelson, Sebastiano Cavallaro, Chu-Li Yi, Donna L. McPhie, Bernard G. Schreurs, P. A. Gusev, Antonella Favit, Ofer Zohar, Jeongho Kim, Sven Beushausen, Giorgio A. Ascoli, John Olds, Rachael L. Neve, Daniel L. Alkon   +13 more
openalex   +1 more source

Calcium compartments in vascular smooth muscle cells as detected by aequorin signal [PDF]

, 1995
Fujio Abe, Minori Mitsui, Hideaki Karaki, Masao Endoh   +3 more
openalex   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Endoplasmic Reticulum Calcium Signaling in Hippocampal Neurons. [PDF]

Biomolecules
Shkryl VM.
europepmc   +1 more source

Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells. [PDF]

, 1995
M. Vajanaphanich, Carsten Schultz, Roger Y. Tsien, Alexis Traynor‐Kaplan, Stephen J. Pandol, Kim E. Barrett   +5 more
openalex   +1 more source

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds

Molecular Oncology, Volume 19, Issue 4, Page 1092-1116, April 2025.
FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana, Paloma Navarro, Iván Hernández, Alejandra Ramos, Ana Montero‐Calle, Pablo Cabezas‐Sainz, Maria J Barrero, Diego Megías, Borja Vilaplana‐Martí, Carolina Epifano, Déborah Gómez‐Dominguez, Sara Monzón, Isabel Cuesta, Laura Sánchez, Rodrigo Barderas, Jesús García‐Donas, Alberto Martín, Ignacio Pérez de Castro   +17 more
wiley   +1 more source