Results 101 to 110 of about 4,759,077 (364)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Machining of Nomex honeycomb composite (NHC) structures is of critical importance in manufacturing parts to the specifications required in the aerospace industry.
Tarik Zarrouk +4 more
doaj +1 more source
Project calculation of the steering mechanism hydraulic servo control in motor vehicles
Hydraulic servo controls are designed to facilitate rotation in place without providing increased ppower to steering wheels. In the initial design phase, the dimensions required for control systems are usually obtained through the calculation of their ...
Zoran Đukan Majkić
doaj +1 more source
Thermochemical Investigations of Associated Solutions: Calculation of Solute-Solvent Equilibrium Constants from Solubility Measurements [PDF]
Article on thermochemical investigations of associated solutions and the calculation of solute-solvent equilibrium constants from solubility ...
McHan, Danny R. +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
ANALYSIS OF CHEMICAL AND PHASE TRANSITIONS OF MULTICOMPONENT ALLOYS UNDER PULSED LASER EXPOSURE IN THE AIR BY METHODS OF CHEMICAL THERMODYNAMICS [PDF]
The article deals with computational thermodynamic method for determination of phase chemical composition of metal alloys surface formed under laser action in the atmosphere, depending on its volume components, conditions of laser exposure and atmosphere
V. P. Veiko +2 more
doaj
Purpose. Obtaining approximate calculation correlations for determination of maximal values of temperature Tm, and pressures Pm at a shock wave and speed vm distribution of a shock wave in the plasma products of air electric explosion (EE) of metall ...
M. I. Baranov, S. V. Rudakov
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Globalization has led to a geographical concentration of economic activities, known as territorialized networks of organizations, especially technopoles.
Adriana Burlea-Schiopoiu, Zineb Znagui
doaj +1 more source
Calculation of the free energy of crystalline solids [PDF]
The prediction of the packing of molecules into crystalline phases is a key step in understanding the properties of solids. Of particular interest is the phenomenon of polymorphism, which refers to the ability of one compound to form crystals with ...
Vasileiadis, Manolis
core +1 more source

