Results 61 to 70 of about 77,245 (243)

Evolution and functional diversity of the Calcium Binding Proteins (CaBPs)

Frontiers in Molecular Neuroscience, 2012
The mammalian central nervous system (CNS) exhibits a remarkable ability to process, store and transfer information. Key to these activities is the use of highly regulated and unique patterns of calcium signals encoded by calcium channels and decoded by ...
Lee P Haynes, Hannah V McCue, Robert D Burgoyne   +2 more
doaj   +1 more source

Surface dynamics in allosteric regulation of protein-protein interactions: modulation of calmodulin functions by Ca2+. [PDF]

PLoS Computational Biology, 2013
Knowledge of the structural basis of protein-protein interactions (PPI) is of fundamental importance for understanding the organization and functioning of biological networks and advancing the design of therapeutics which target PPI.
Yosef Y Kuttner, Tal Nagar, Stanislav Engel   +2 more
doaj   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

The Phytophthora RXLR Effector Avrblb2 Modulates Plant Immunity by Interfering With Ca2+ Signaling Pathway

Frontiers in Plant Science, 2019
In plants, subcellular fluctuations in Ca2+ ion concentration are among the earliest responses to biotic and abiotic stresses. Calmodulin, which is a ubiquitous Ca2+ ion sensor in eukaryotes, plays a major role in translating these Ca2+ signatures to ...
Zunaira Afzal Naveed, Shaheen Bibi, Gul Shad Ali   +2 more
doaj   +1 more source

Plant Kinesin-Like Calmodulin Binding Protein Employs Its Regulatory Domain for Dimerization. [PDF]

PLoS ONE, 2013
Kinesin-like calmodulin binding protein (KCBP), a Kinesin-14 family motor protein, is involved in the structural organization of microtubules during mitosis and trichome morphogenesis in plants.
Maia V Vinogradova, Galina G Malanina, Joshua S Waitzman, Sarah E Rice, Robert J Fletterick   +4 more
doaj   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Single-step purification of intrinsic protein complexes in Saccharomyces cerevisiae using regenerable calmodulin resin

MethodsX, 2018
Characterization of protein- protein interactions is a vital aspect of molecular biology as multi-protein complexes are the functional units of cellular processes and defining their interactions provides valuable insights into their function based on a ...
Urvi Bhojoo, Kyle K. Biggar
doaj   +1 more source

Calmodulin-binding transcription activator (CAMTA) genes family: Genome-wide survey and phylogenetic analysis in flax (Linum usitatissimum).

PLoS ONE, 2020
Flax (Linum usitatissimum) is a member of family linaceae with annual growth habit. It is included among those crops which were domesticated very early and has been used in development related studies as a model plant.
Essa Ali, Mohammad Ammar Raza, Ming Cai, Nazim Hussain, Ahmad Naeem Shahzad, Mubshar Hussain, Murtaza Ali, Syed Asad Hussain Bukhari, Peilong Sun   +8 more
doaj   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

iMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei, Tengxiang Lian, Liying Chen, Lanxiang Wang, Junjie Ye, Xiaofang Yao, Shilong Duan, Ziyu Lu, Jinji Tu, Hongfu Li, Xin‐Yue Xu, Jie Zhou, Junliang He, Feiying Zhu, Paola Bonfante, Lam‐Son Phan Tran, Zhiqiang Pang, Xin Zhou, Zhihui Xu, Lin Zhang, Mengcen Wang, Xiaolin Wang, Chang‐Fu Tian, Yong‐Xin Liu, Kai Sun, Ertao Wang, Xianan Xie   +26 more
wiley   +1 more source

The effect of macromolecular crowding, ionic strength and calcium binding on calmodulin dynamics.

PLoS Computational Biology, 2011
The flexibility in the structure of calmodulin (CaM) allows its binding to over 300 target proteins in the cell. To investigate the structure-function relationship of CaM, we combined methods of computer simulation and experiments based on circular ...
Qian Wang, Kao-Chen Liang, Arkadiusz Czader, M Neal Waxham, Margaret S Cheung   +4 more
doaj   +1 more source