Results 161 to 170 of about 131,283 (255)

Structures of the UBR4 complex reveal a giant arena to capture diverse substrates for ubiquitin chain elongation

open access: yesThe FEBS Journal, EarlyView.
This review summarizes recent structures of the UBR4 complex, a giant E4 ubiquitin ligase which recognizes proteins with pre‐existing ubiquitin modifications and marks them for degradation. The UBR4 complex uses a large arena lined with substrate interaction modules to select features on ubiquitinated substrates, such as the presence of N‐degrons or ...
Daniel B. Grabarczyk, Tim Clausen
wiley   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

open access: yesInsect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto   +2 more
wiley   +1 more source

Norroa™ as a dsRNA biopesticide for <i>Varroa destructor</i>: insights from New Zealand research on mode of action, field efficacy, non-target effects, and social acceptance. [PDF]

open access: yesFront Insect Sci
Lester PJ   +9 more
europepmc   +1 more source

Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity

open access: yesImmunology, EarlyView.
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez   +3 more
wiley   +1 more source

Revising NHE-1: From Cardiac Homeostasis to Heart Failure and Future Drug Development. [PDF]

open access: yesCell Biochem Funct
Bouratzis V   +8 more
europepmc   +1 more source

TaHDA1‐mediated histone and non‐histone deacetylation orchestrates drought tolerance in wheat

open access: yesJournal of Integrative Plant Biology, EarlyView.
The histone deacetylase TaHDA1 is a key regulator linking histone and non‐histone deacetylation with drought adaptation and a potential target for improving drought resilience and grain nutritional quality in wheat. ABSTRACT Drought stress severely constrains wheat (Triticum aestivum L.) growth and productivity.
Jinpeng Li   +21 more
wiley   +1 more source

Duckweeds under salt stress: a meta‐analysis of growth inhibition in relation to morphological and physiological traits and a systematic review of molecular responses

open access: yesNew Phytologist, EarlyView.
Salinity reduces duckweed growth responses. Summary Salinity is one of the main environmental factors limiting the performance of duckweeds and despite growing ecological and biotechnological interest in these macrophytes, there is a lack of quantitative analyses of their responses to sodium chloride.
Saimon Branco Bueno   +7 more
wiley   +1 more source

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