Results 181 to 190 of about 131,283 (255)

Proteomic Snapshots of Structural Cross-Linking Rearrangements in Ca^2<b>+</b>/Calmodulin-Dependent Kinase-1-Delta Associated with Its Regulation by ATP, Ca^2<b>+</b>/Calmodulin, and Reduction Potential. [PDF]

J Proteome Res
Mbabala L, Tshililo NO, Vlok M, Vendrell I, Fischer R, Tabb DL, Trieber CA, Adra TRC, Overduin M, Butterworth S, Kenyon CP.   +10 more
europepmc   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

Experimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou, Paschalis Karakasis, Panagiotis Theofilis, Konstantinos Pamporis, Panayotis K. Vlachakis, Anastasios Apostolos, Nikolaos Ktenopoulos, Barbara Fyntanidou, Efstratios Karagiannidis, Dimitrios Patoulias, Antonios P Antoniadis, Nikolaos Fragakis   +11 more
wiley   +1 more source

Verapamil Reduces Collagen Synthesis to Alleviate Ureteral Scar Formation by Inhibiting KDM1A-Mediated Epigenetic Silencing of SESN2.

Kidney Blood Press Res
He J, Li J, Wu X, Zhu Z, Chen J, Lu Q, Tang Z, Li Y, Zeng M.   +8 more
europepmc   +1 more source

CALM1, CALM2, and CALM3 expression and translation efficiency provide insight into the severity of calmodulinopathy. [PDF]

Europace
Christiansen SNN, Jacobsen SB, Andersen JD, Cui Y, Li W, Staehr C, Andersen MM, Crotti L, Spazzolini C, Schwartz PJ, Nyegaard M, Overgaard MT.   +11 more
europepmc   +1 more source

Ageing alters cysteine oxidation‐regulated redox signalling in skeletal muscle: Integrative omics and AI‐based structural predictions

Experimental Physiology, EarlyView.
Abstract Ageing is associated with loss of skeletal muscle mass and strength (sarcopenia) and disrupted redox homeostasis. Redox signalling is essential for muscle adaptation, yet the mechanisms by which ageing disrupts cysteine‐based regulation are poorly defined. The drivers of site‐specific reactivity and signalling specificity in aged muscle remain
Ufuk Ersoy, Malcolm J. Jackson
wiley   +1 more source

Cryo-EM structure of soluble VPS13C suggests its regulation by a conformational switch and by calmodulin. [PDF]

Mol Cell
Li D, Wang X, Hao H, Eden J, Hu B, Walsh EE, Parson MAH, Hamill S, Li Y, Chen G, Burke JE, De Camilli P, Reinisch KM.   +12 more
europepmc   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

Experimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera, Jose Lozano‐Meca, Miguel López‐Moreno, Edgar Simón Sancho‐Haro, Mario Muñoz‐López, Eneko Baz‐Valle, José Francisco López‐Gil, Rodrigo Yáñez‐Sepúlveda, Vicente Javier Clemente‐Suárez   +8 more
wiley   +1 more source

Publisher Correction: The CNP analogue vosoritide mediates PDE2-sensitive anti-arrhythmogenic effects in mouse hearts with STZ-induced type 1 diabetes. [PDF]

Basic Res Cardiol
Firneburg R, Tergau K, Cachorro E, Schubert M, Dhara A, Luo X, Klapproth E, Guan K, El-Armouche A, Kämmerer S.   +9 more
europepmc   +1 more source

TMEM16A channel signalling microdomains in the regulation of vascular function

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of TMEM16A channel signalling microdomains. Calcium influx or calcium release from the endoplasmic/sarcoplasmic reticulum (ER/SR) activates TMEM16A channels through interactions with regulatory proteins in vascular smooth muscle cells or endothelial cells. TMEM16A channel activation drives chloride efflux,
Fênix Araujo, Swapnil K. Sonkusare
wiley   +1 more source

Genome-wide identification and characterization of CaM and CML gene family in chickpea (Cicer arietinum L.). [PDF]

Sci Rep
Swain B, Gupta P, Yadav D.
europepmc   +1 more source