Results 191 to 200 of about 12,830 (266)

Corporate Power in a Multistakeholder World: Venue Hopping and the Multilevel Politics of Ultra‐Processed Food

open access: yesRegulation &Governance, EarlyView.
ABSTRACT The regulation of business is increasingly characterized by “soft” governance regimes that blur the boundaries of public and private authority, as signaled by the rapid proliferation of multistakeholder initiatives in global governance. This article explores how the spread of multistakeholderism creates opportunities for new forms of strategic
Rob Ralston, Ben Hawkins
wiley   +1 more source

Avoid Confusion! Does Survival Processing Shape the Spontaneous Use of Learning Strategies for Distinguishing Edible and Poisonous Mushroom Twins?

open access: yesTopics in Cognitive Science, EarlyView.
Abstract Hunter‐gatherers faced the survival threat of confusing edible mushrooms with their poisonous twins, imposing selection pressure on those who failed to detect subtle visual differences. Grounded in the ancestral priorities framework, which posits that the human mind is adapted to handle prehistoric challenges, we investigated whether humans ...
Roman Abel
wiley   +1 more source

Adipose tissue‐derived small extracellular vesicles and blood–brain barrier function in adults with overweight and obesity

open access: yesExperimental Physiology, EarlyView.
Abstract Obesity is associated with adverse changes in brain structure and function, in part, through crosstalk between adipose tissue (AT) and the brain. AT releases small extracellular vesicles (sEV) that can cross the blood–brain barrier (BBB) and modulate multiple pathophysiological pathways, including BBB function; however, this has never been ...
Shalini Mishra   +6 more
wiley   +1 more source

Understanding stressors in combination: a continued challenge for human performance

open access: yesExperimental Physiology, EarlyView.
Abstract Personnel within occupational employment (e.g., military/emergency services) are exposed to various stressors concurrently including psychological, cognitive, physical and environmental. Historically, stressors have been considered and studied in isolation which is not representative of reality.
Katrina Hinde   +2 more
wiley   +1 more source

Acute ketone monoester ingestion lowers resting cerebral blood flow: a randomized cross‐over trial

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This double‐blind, placebo‐controlled, randomized cross‐over trial investigated the effects of ketone monoester (KME) ingestion on resting cerebral blood flow (CBF) in young adults. We demonstrate that KME supplementation lowers CBF in a dose‐dependent manner over 2‐houra post‐ingestion, whereas CBF remained unchanged following ...
Aedan J. Rourke   +7 more
wiley   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Astrocyte‐derived lactate enhances neuronal NMDA receptor (NMDAR) function and synaptic plasticity through a redox‐ and CaMKII‐dependent mechanism. Lactate enters neurons via monocarboxylate transporters (MCTs) and is oxidized by lactate dehydrogenase (LDH) to pyruvate, generating NADH and increasing the intracellular NADH/NAD ...
Hubert Fiumelli   +13 more
wiley   +1 more source

Inhibitory Effect of Lidocaine on Duodenal Peristalsis During Endoscopic Retrograde Cholangiopancreatography: A Multicenter, Randomized Controlled Trial (With Video)

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Conventional antispasmodics used during endoscopic retrograde cholangiopancreatography (ERCP), such as hyoscine butylbromide and glucagon, are often contraindicated in elderly patients with comorbidities. This trial aimed to assess the efficacy of lidocaine for inhibiting duodenal peristalsis during ERCP.
Masato Suzuki   +11 more
wiley   +1 more source

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