Results 21 to 30 of about 28,252 (277)
Antibodies, 2021 Calreticulin is a chaperone protein, which is associated with myeloproliferative diseases. In this study, we used resin-bound peptides to characterize two monoclonal antibodies (mAbs) directed to calreticulin, mAb FMC 75 and mAb 16, which both have ...
Ann Christina Bergmann +6 more
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Calreticulin Mediates Nerve Growth Factor-Induced Neuronal Differentiation [PDF]
, 2014 The nerve growth factor (NGF)/TrkA-signaling is necessary for neural development, and its abnormality has been tightly associated with the tumorigenesis of various cancers originated from the nervous system. The characterization of key molecules involved
Shih, Yu-Yin;Nakagawara, Akira;Lee, Hsinyu;Juan, Hsueh-Fen;Jeng, Yung-Ming;Lin, Dong-Tsamn;Yang, Yung-Li;Tsay, Yeou-Guang;Huang, Min-Chuan;Pan, Chien-Yuan;Hsu, Wen-Ming;Liao, Yung-Feng +1 more
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s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin [PDF]
, 1992 Cyclophilins (cyclosporin A-binding proteins) are conserved, ubiquitous, and abundant proteins that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins in vitro.
Arber, S. +6 more
core +1 more source
Calreticulin Regulates SARS-CoV-2 Spike Protein Turnover and Modulates SARS-CoV-2 Infectivity
Cells, 2023 Cardiovascular complications are major clinical hallmarks of acute and post-acute coronavirus disease 2019 (COVID-19). However, the mechanistic details of SARS-CoV-2 infectivity of endothelial cells remain largely unknown.
Nader Rahimi +7 more
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Pathology & Oncology Research, 2013 Calreticulin (CRT) as a multi-functional endoplasmic reticulum protein is involved in a spectrum of cellular processes which ranges from calcium homeostasis and chaperoning to cell adhesion and finally malignant formation and progression. Previous studies have shown a contributing role for CRT in a range of different cancers.
Mohammadreza, Zamanian +3 more
openaire +2 more sources
Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transition [PDF]
, 2017 Peritoneal dissemination is a major clinical obstacle in gastrointestinal cancer therapy, and it accounts for the majority of cancer-related mortality. Calreticulin (CRT) is over-expressed in gastric tumors and has been linked to poor prognosis.
Liu, Shin G-Hwa;Lee, Wen-Jane;Lai, De-Wei;Wu, Sheng-Mao;Liu, Chia-Yu;Tien, Hsing-Ru;Chiu, Chien-Shan;Peng, Yen-Chun;Jan, Yee-Jee;Chao, Te-Hsin;Pan, Hung-Chuan;Sheu, Meei-Ling +1 more
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Frontiers in Oncology, 2015 Calreticulin is recognized as one of pivotal damage-associated molecular pattern (DAMP) molecules alerting the host of the presence of distressed cells. In this role, calreticulin becomes exposed on the surface of tumor cells treated by several types of
Mladen eKorbelik +4 more
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COUP-TF1 antagonizes Nkx25-mediated activation of the calreticulin gene during cardiac development [PDF]
, 2001 Calreticulin, a Ca2+ binding chaperone of the endoplasmic reticulum, is also highly expressed in the embryonic heart, and knockout of the calreticulin gene is lethal during embryogenesis because of impaired cardiac development.
Agellon, Luis B. +8 more
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Nature Communications, 2023 In myeloproliferative neoplasms, frameshift mutants of calreticulin turn into rogue cytokines by inducing constitutive activation of the Thrombopoietin Receptor (TpoR).
Nicolas Papadopoulos +12 more
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Stem Cell Reports, 2017 Calreticulin, a multifunctional endoplasmic reticulum resident protein, is required for TGF-β-induced epithelial-to-mesenchymal transition (EMT) and subsequent cardiomyogenesis. Using embryoid bodies (EBs) derived from calreticulin-null and wild-type (WT)
Fereshteh Karimzadeh, Michal Opas
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