Results 41 to 50 of about 28,252 (277)

X-ray structure of the human calreticulin globular domain reveals a peptide-binding area and suggests a multi-molecular mechanism.

open access: yesPLoS ONE, 2011
In the endoplasmic reticulum, calreticulin acts as a chaperone and a Ca(2+)-signalling protein. At the cell surface, it mediates numerous important biological effects.
Anne Chouquet   +6 more
doaj   +1 more source

Silver nanoparticles induce a non-immunogenic tumor cell death

open access: yesJournal of Immunotoxicology, 2023
Immunogenic cell death (ICD) is a form of cell death characterized by the release of danger signals required to trigger an adaptive immune response against tumor-associated antigens.
Maritza Roxana Garcia Garcia   +12 more
doaj   +1 more source

Suppression of Cx43 promoter by calreticulin. [PDF]

open access: yes, 2013
(A) A schematic representation of calreticulin and calreticulin domains. CRT, calreticulin full length tagged with HA epitope; CRT-PC, P+C domain of calreticulin tagged with HA epitope. HA, hemagglutinin; KDEL, ER retrieval amino acid sequence.
Wattamon Srisakuldee (380080)   +13 more
core   +1 more source

Expression and clinical implication of calreticulin in diffuse large B-cell lymphoma

open access: yesZhongguo aizheng zazhi, 2020
Background and purpose: Lymphoma is the most common hematopoietic malignant tumor. B-cell non-Hodgkin’s lymphoma (NHL) accounts for more than 90% of lymphomas. The most common subtype in B-cell NHL is diffuse large B-cell lymphoma (DLBCL).
葛晓雯   +8 more
doaj  

Calreticulin as A Novel Potential Metastasis-Associated Protein in Myxoid Liposarcoma, as Revealed by Two-Dimensional Difference Gel Electrophoresis

open access: yesProteomes, 2019
Myxoid liposarcoma (MLS) is a mesenchymal malignancy. To identify innovate seeds for clinical applications, we examined the proteomes of primary tumor tissues from 10 patients with MLS with different statuses of postoperative metastasis.
Takashi Tajima   +4 more
doaj   +1 more source

Growing Maize Root: Lectins Involved in Consecutive Stages of Cell Development

open access: yesPlants, 2022
Proteins that carry specific carbohydrate-binding lectin domains have a great variety and are ubiquitous across the plant kingdom. In turn, the plant cell wall has a complex carbohydrate composition, which is subjected to constant changes in the course ...
Aliya Aglyamova   +4 more
doaj   +1 more source

CALR (calreticulin) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
Calreticulin (CALR) is a multifunctional protein involved in molecular chaperoning and calcium homeostasis. CALR has also been associated with proliferation, cell cycle progression, migration, invasion and anoikis resistance in cancer cells. The prognostic impact of CALR expression is yet to be elucidated, however in some types of cancer, high CALR ...
Machado-Neto, Joao Agostinho   +2 more
openaire   +2 more sources

The Novel Type 1 Fimbriae FimH Receptor Calreticulin Plays a Role in Salmonella Host Specificity

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
It was suggested that minor differences in the structure of FimH are most likely associated with differences in its adhesion specificities and may determine the tropism of various Salmonella serovars to different species and tissues.
Krzysztof Grzymajlo   +7 more
doaj   +1 more source

Calreticulin and GRP78 as Bioindicators for the Diagnosis of COVID-19 Pneumonia [PDF]

open access: yes
Background: Coronavirus Disease 2019 (COVID-19) has been reported by the World Health Organization as a global health issue, leading to severe respiratory infections in humans. Recent studies have shown that endoplasmic reticulum stress can contribute to
Şükrü Koçkan, Berrin Öztaş
core   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

open access: yesAdvanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan   +10 more
wiley   +1 more source

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