Results 41 to 50 of about 30,178 (280)
Expression and clinical implication of calreticulin in diffuse large B-cell lymphoma
Zhongguo aizheng zazhi, 2020 Background and purpose: Lymphoma is the most common hematopoietic malignant tumor. B-cell non-Hodgkin’s lymphoma (NHL) accounts for more than 90% of lymphomas. The most common subtype in B-cell NHL is diffuse large B-cell lymphoma (DLBCL).
葛晓雯 +8 more
doaj
The Novel Type 1 Fimbriae FimH Receptor Calreticulin Plays a Role in Salmonella Host Specificity
Frontiers in Cellular and Infection Microbiology, 2017 It was suggested that minor differences in the structure of FimH are most likely associated with differences in its adhesion specificities and may determine the tropism of various Salmonella serovars to different species and tissues.
Krzysztof Grzymajlo +7 more
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, 2017 Peritoneal dissemination is a major clinical obstacle in gastrointestinal cancer therapy, and it accounts for the majority of cancer-related mortality. Calreticulin (CRT) is over-expressed in gastric tumors and has been linked to poor prognosis.
Liu, Shin G-Hwa;Lee, Wen-Jane;Lai, De-Wei;Wu, Sheng-Mao;Liu, Chia-Yu;Tien, Hsing-Ru;Chiu, Chien-Shan;Peng, Yen-Chun;Jan, Yee-Jee;Chao, Te-Hsin;Pan, Hung-Chuan;Sheu, Meei-Ling +1 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Calreticulin and GRP78 as Bioindicators for the Diagnosis of COVID-19 Pneumonia [PDF]
Background: Coronavirus Disease 2019 (COVID-19) has been reported by the World Health Organization as a global health issue, leading to severe respiratory infections in humans. Recent studies have shown that endoplasmic reticulum stress can contribute to
Şükrü Koçkan, Berrin Öztaş
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Advanced Functional Materials, EarlyView.Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang +16 more
wiley +1 more source
Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy
Frontiers in Immunology, 2017 As a multicellular parasitic nematode, Trichinella spiralis regulates host immune responses by producing a variety of immunomodulatory molecules to escape from host immune attack, but the mechanisms underlying the immune evasion are not well understood ...
Limei Zhao +13 more
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Antibodies, 2021 Calreticulin is a chaperone protein, which is associated with myeloproliferative diseases. In this study, we used resin-bound peptides to characterize two monoclonal antibodies (mAbs) directed to calreticulin, mAb FMC 75 and mAb 16, which both have ...
Ann Christina Bergmann +6 more
doaj +1 more source
COUP-TF1 antagonizes Nkx25-mediated activation of the calreticulin gene during cardiac development
, 2001 Calreticulin, a Ca2+ binding chaperone of the endoplasmic reticulum, is also highly expressed in the embryonic heart, and knockout of the calreticulin gene is lethal during embryogenesis because of impaired cardiac development.
Agellon, Luis B. +8 more
core +1 more source
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source