Results 51 to 60 of about 28,252 (277)
Advanced Materials, EarlyView.Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan +6 more
wiley +1 more source
Polypeptide binding properties of the chaperone calreticulin. [PDF]
, 2000 Udgivelsesdato: 2000-MayCalreticulin is a highly conserved eukaryotic ubiquitious protein located mainly in the endoplasmic reticulum. Two major characteristics of calreticulin are its chaperone activity and its lectin properties, but its precise ...
Jørgensen, C S +4 more
core +1 more source
Flexible Wide Bandgap Electrode System for In situ Cell Sensing and Irreversible Electroporation
Advanced Materials Interfaces, EarlyView.The paper reports the design and wafer‐level microfabrication of a long‐lived, flexible 3C‐SiC electrode capable of sensitive and in situ cell sensing, as well as electroporation ablation. The work demonstrates a biocompatible and durable electrode platform that can perform reliable electrical interfacing with biological tissues over extended periods ...
Minh Anh Huynh +3 more
wiley +1 more source
Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy
Frontiers in Immunology, 2017 As a multicellular parasitic nematode, Trichinella spiralis regulates host immune responses by producing a variety of immunomodulatory molecules to escape from host immune attack, but the mechanisms underlying the immune evasion are not well understood ...
Limei Zhao +13 more
doaj +1 more source
Down-regulation of calreticulin promotes apoptosis in hepatic stellate cells
Di-san junyi daxue xuebao, 2021 Objective To investigate the effect of calreticulin (CALR) down-regulation on apoptosis and endoplasmic reticulum stress (ERS) pathway in hepatic stellate cells (HSCs).
DAI Linyu +3 more
doaj +1 more source
Calreticulin expression in canine placenta [PDF]
, 2019 Publisher Copyright: © 2019, Universidad de la Frontera. All rights reserved.The placenta is an embryonic organ present in mammals, whose main functions are the exchange of nutrients and gases and to protect the fetus from potential immune damage ...
Katherine Weinberger, S. +4 more
core +1 more source
Advanced Science, EarlyView.Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
Bioengineering & Translational Medicine, 2023 The development of an optimal treatment modality to improve the therapeutic outcome of breast cancer patients is still difficult. Poor antigen presentation to T cells is a major challenge in cancer immunotherapy.
Asmita Banstola +5 more
doaj +1 more source
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Functional conservation of calreticulin in Euglena gracilis [PDF]
, 1998 Calreticulin is the major high capacity, low affinity Ca2+ binding protein localized within the endoplasmic reticulum. It functions as a reservoir for triggered release of Ca2+ by the endoplasmic reticulum and is thus integral to eukaryotic signal ...
NAVAZIO L +9 more
core +3 more sources