Results 31 to 40 of about 30,178 (280)
Calreticulin couples with immune checkpoints in pancreatic cancer
Clinical and Translational Medicine, 2020 Although immune checkpoint blockade is considered to be the dominant approach in future cancer immunotherapy, whether it will apply to pancreatic cancer remains largely unknown.
Xing Huang +4 more
doaj +1 more source
Silver nanoparticles induce a non-immunogenic tumor cell death
Journal of Immunotoxicology, 2023 Immunogenic cell death (ICD) is a form of cell death characterized by the release of danger signals required to trigger an adaptive immune response against tumor-associated antigens.
Maritza Roxana Garcia Garcia +12 more
doaj +1 more source
European Journal of Biochemistry, 2003 Increasing evidence suggests that melatonin can exert some effect at nuclear level. Previous experiments using binding techniques clearly showed the existence of specific melatonin binding sites in cell nucleus of rat liver. To further identify these sites, nuclear extracts from rat hepatocytes were treated with different percentages of ammonium ...
Manuel, Macías +6 more
openaire +2 more sources
PLoS ONE, 2011 In the endoplasmic reticulum, calreticulin acts as a chaperone and a Ca(2+)-signalling protein. At the cell surface, it mediates numerous important biological effects.
Anne Chouquet +6 more
doaj +1 more source
Growing Maize Root: Lectins Involved in Consecutive Stages of Cell Development
Plants, 2022 Proteins that carry specific carbohydrate-binding lectin domains have a great variety and are ubiquitous across the plant kingdom. In turn, the plant cell wall has a complex carbohydrate composition, which is subjected to constant changes in the course ...
Aliya Aglyamova +4 more
doaj +1 more source
Calreticulin Regulates VEGF-A in Neuroblastoma Cells
, 2017 Calreticulin (CRT) has been previously correlated with the differentiation of neuroblastoma (NB), implying a favorable prognostic factor. Vascular endothelial growth factor (VEGF) has been reported to participate in the behavior of NB.
Weng, Wen-Chin;Lin, Kuan-Hung;Wu, Pei-Yi;Lu, Yi-Chien;Weng, Yi-Cheng;Wang, Bo-Jeng;Liao, Yung-Feng;Hsu, Wen-Ming;Lee, Wang-Tso;Lee, Hsinyu +1 more
core +1 more source
Proteomes, 2019 Myxoid liposarcoma (MLS) is a mesenchymal malignancy. To identify innovate seeds for clinical applications, we examined the proteomes of primary tumor tissues from 10 patients with MLS with different statuses of postoperative metastasis.
Takashi Tajima +4 more
doaj +1 more source
Calreticulin Mediates Nerve Growth Factor-Induced Neuronal Differentiation
, 2014 The nerve growth factor (NGF)/TrkA-signaling is necessary for neural development, and its abnormality has been tightly associated with the tumorigenesis of various cancers originated from the nervous system. The characterization of key molecules involved
Shih, Yu-Yin;Nakagawara, Akira;Lee, Hsinyu;Juan, Hsueh-Fen;Jeng, Yung-Ming;Lin, Dong-Tsamn;Yang, Yung-Li;Tsay, Yeou-Guang;Huang, Min-Chuan;Pan, Chien-Yuan;Hsu, Wen-Ming;Liao, Yung-Feng +1 more
core +1 more source
Identification of a Novel Antibacterial Function of Mammalian Calreticulin
BiomoleculesCalreticulin is a highly conserved and multifunctional molecular chaperone ubiquitously expressed in humans and animals. Beyond its well-established roles in calcium homeostasis, protein folding, and immune regulation, recent studies in aquatic species ...
Yichao Ma +4 more
doaj +1 more source
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2018 Calreticulin (CALR) is a multifunctional protein involved in molecular chaperoning and calcium homeostasis. CALR has also been associated with proliferation, cell cycle progression, migration, invasion and anoikis resistance in cancer cells. The prognostic impact of CALR expression is yet to be elucidated, however in some types of cancer, high CALR ...
Machado-Neto, Joao Agostinho +2 more
openaire +2 more sources