Results 131 to 140 of about 304,977 (339)
Advanced Science, EarlyView.An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz +10 more
wiley +1 more source
THE VALUE OF PRECONDITIONING PROGRAMS IN BEEF PRODUCTION SYSTEMS [PDF]
Net returns to feeding were calculated for preconditioning. The added value to cattle feeders, without accounting for death loss, from purchasing preconiditioned calves over calves of unknown origin is $46.83/head and $49.54/head for the CPH and GT ...
Roeber, D.L., Umberger, Wendy J.
core +1 more source
Duration of unassisted swimming activity for spotted dolphin (Stenella attenuata) calves: implications for mother-calf separation during tuna purse-seine sets [PDF]
, 2006 Size-related differences in power production and swim speed duration may contribute to the observed deficit of nursing calves in relation to lactating females killed in sets by tuna purse-seiners in the eastern tropical Pacific Ocean (ETP).
Edwards, Elizabeth F.
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Advanced Science, EarlyView.A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu +9 more
wiley +1 more source
Advanced Science, EarlyView.Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu +10 more
wiley +1 more source
Thermic dehorning and ear tagging as atypical portals of entry of Clostridium tetani in ruminants [PDF]
, 2011 This paper describes two infections with Clostridium tetani (C. tetani). One outbreak occurred after dehorning of calves, the second infection happened after ear tagging of a goat.
Boyen, Filip +6 more
core +1 more source
USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer
Advanced Science, EarlyView.USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen +9 more
wiley +1 more source
DAIRY HERD MANAGEMENT PRACTICES FOCUSING ON PREWEANED HEIFERS [PDF]
The National Dairy Heifer Evaluation Project ( NDHEP ) was conducted by the National Animal Health Monitoring System (NAHMS ) from April 1991 through July 1992 with the assistance of 1,811 producers from 28 states.
Ott, Stephen L.
core +1 more source
Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks
Advanced Science, EarlyView.This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen +11 more
wiley +1 more source
Suckling as an alternative rearing system for replacement calves on dairy farms [PDF]
, 2004 The aim is to develop an alternative calf rearing system for replacement calves that will improve animal welfare on dairy farms and meets the requirements of farmers in terms of practicality and cost. On the dairy farms that make use of a suckling system
Langhout, Jos, Wagenaar, Jan-Paul
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