Results 1 to 10 of about 51,149 (268)
Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36) [PDF]
AII amacrine cells are essential interneurons of the primary rod pathway and transmit rod-driven signals to ON cone bipolar cells to enable scotopic vision.
Stephan Tetenborg +7 more
doaj +5 more sources
Integrated mechanisms of CaMKII-dependent ventricular remodeling
CaMKII has been shown to be activated during different cardiac pathological processes, and CaMKII-dependent mechanisms contribute to pathological cardiac remodeling, cardiac arrhythmias and contractile dysfunction during heart failure.
Johannes Backs
exaly +3 more sources
Ser-Thr phosphatases in the rat brain that dephosphorylate phospho-Ser(1291)-GluN2A subunit of glutamate receptor [PDF]
N-methyl-D-aspartate receptors (NMDARs), are one of the major ionotropic glutamate receptors found in excitatory synapses which play a key role in glutamatergic synaptic transmission.
R. R. Prabhu
doaj +1 more source
Summary: Aβ bears homology to the CaMKII regulatory domain, and peptides derived from this domain can bind and disrupt the CaMKII holoenzyme, suggesting that Aβ could have a similar effect.
Carolyn Nicole Brown +4 more
doaj +1 more source
Exploring Excitotoxicity and Regulation of a Constitutively Active TRP Ca2+ Channel in Drosophila
Unregulated Ca2+ influx affects intracellular Ca2+ homoeostasis, which may lead to neuronal death. In Drosophila, following the activation of rhodopsin the TRP Ca2+ channel is open to mediate the light-dependent depolarization.
Bih-Hwa Shieh +2 more
doaj +1 more source
Ca2+/calmodulin-dependent protein kinase II (CaMKII), which is involved in the calcium signaling pathway, is an important regulator of cancer cell proliferation, motility, growth, and metastasis.
Jumi Kim +10 more
doaj +1 more source
Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy. [PDF]
Activation of Ca2+/Calmodulin protein kinase II (CaMKII) is an important step in signaling of cardiac hypertrophy. The molecular mechanisms by which CaMKII integrates with other pathways in the heart are incompletely understood.
Ersilia Cipolletta +15 more
doaj +1 more source
Locally-Induced CaMKII Translocation Requires Nucleotide Binding
Calcium-calmodulin-dependent protein kinase (CaMKII) is a molecule involved in several cell processes including plasticity related to learning and memory. Activation of NMDA-type glutamate receptors results in translocation of CaMKII to synapses. However,
Zachary T. Fitzgerald +1 more
doaj +1 more source
The dorsal striatum is important for the development of drug addiction; however, the role of dopamine D1 receptor (D1R) expressing medium-sized spiny striatonigral (direct pathway) neurons (D1-MSNs) in regulating excessive methamphetamine intake remains ...
Robert J. Oliver +3 more
doaj +1 more source
CaMKII regulates neuromuscular activity and survival of the human blood fluke Schistosoma mansoni
Calcium/calmodulin dependant protein kinase II (CaMKII), an important transducer of Ca2+ signals, orchestrates multiple cellular functions in animals.
Natasha L. Hirst +2 more
doaj +1 more source

