Results 281 to 290 of about 6,565,578 (347)

GPR81 Regulates MCT1 Membrane Translocation Through a PKA-Dependent Signaling Pathway in Rat Podocytes. [PDF]

Int J Mol Sci
Grochowalska K, Szrejder M, Audzeyenka I, Piwkowska A.   +3 more
europepmc   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Pharmacological Mechanisms of Active Constituents from Traditional Chinese Medicine for Vitiligo Treatment. [PDF]

Pharmaceuticals (Basel)
Hamiti A, Geng Y, Huang P, Xie J, Cui T.
europepmc   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

The Bile Acid Signaling Axis: Deciphering the Roles of FXR and TGR5 in Hepatic Steatosis, Fibrosis, and Cancer. [PDF]

Pharmacol Res Perspect
Liu J, Sun K, Liu H, Zhu M, Li C, He Y, Qin L.   +6 more
europepmc   +1 more source

Publisher Correction: The CNP analogue vosoritide mediates PDE2-sensitive anti-arrhythmogenic effects in mouse hearts with STZ-induced type 1 diabetes. [PDF]

Basic Res Cardiol
Firneburg R, Tergau K, Cachorro E, Schubert M, Dhara A, Luo X, Klapproth E, Guan K, El-Armouche A, Kämmerer S.   +9 more
europepmc   +1 more source

Neural-tumor interactions: bidirectional regulatory mechanisms and nervous system-targeted tumor therapeutic strategies. [PDF]

Biomark Res
Huang Y, Tong T, Zeng Z, Tan M, Qu H, Xiong W.   +5 more
europepmc   +1 more source

Orai1-mediated Ca²⁺ entry regulates lipolysis and mitochondrial activation in brown adipose thermogenesis. [PDF]

Exp Mol Med
Kim S, Nguyen PA, Park KS, Cha SK, Namkung J.   +4 more
europepmc   +1 more source

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Regulation of ion channels by cAMP-dependent protein kinase and A-kinase anchoring proteins

Current Opinion in Neurobiology, 1998
Subcellular targeting of the cAMP-dependent protein kinase is achieved, in part, through association with A-kinase anchoring proteins (AKAPs). Recent evidence suggests that specific AKAPs direct the kinase to submembrane sites to facilitate phosphorylation and modulation of a variety of ion channels.
William A. Catterall, John D. Scott, Peter C Gray   +2 more
exaly   +3 more sources

Dynamics of cAMP-Dependent Protein Kinase

Chemical Reviews, 2001
D A, Johnson, P, Akamine, E, Radzio-Andzelm, M, Madhusudan, S S, Taylor   +4 more
openaire   +3 more sources