Results 51 to 60 of about 6,565,578 (347)
Cyclic adenosine 3′,5′monophosphate (cAMP) regulated element binding protein (CREB) is a transcription factor involved in many different signaling processes including memory storage and retrieval.
Erik Maronde
doaj +1 more source
Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase [PDF]
eEF2K [eEF2 (eukaryotic elongation factor 2) kinase] phosphorylates and inactivates the translation elongation factor eEF2. eEF2K is not a member of the main eukaryotic protein kinase superfamily, but instead belongs to a small group of so-called ...
Hussain, Nusrat +16 more
core +1 more source
We investigated the effects of specific inhibitors of cAMP-dependent protein kinase (PKA) and cGMP-dependent protein kinase (PKG) on the inhibitory activity of phosphodiesterase (PDE) type 4 inhibitors and of the cell permeable analogue of cAMP, db-cAMP ...
A. Hichami +5 more
doaj +1 more source
We report the results of experiments which support the hypothesis that, in mouse oocytes, a decrease in intraoocyte cyclic AMP (cAMP) initiates meiotic maturation; oocytes microinjected with cyclic nucleotide phosphodiesterase (PDE) underwent germinal ...
E. Bornslaeger, P. Mattei, R. M. Schultz
semanticscholar +1 more source
Regulation of protein kinase B (PKB/Akt) by DNA-dependent protein kinase (DNA-PK) under physiological conditions [PDF]
The serine/threonine protein kinase B (PKB/Akt) is a downstream effector of phosphatidylinositol 3-kinase (PI3K) and a major regulator of a variety of cellular processes, including metabolism, transcription, survival, proliferation, and growth.
Sürücü, Banu
core +1 more source
Regulation of Cardiac PKA Signaling by cAMP and Oxidants
Pathologies, such as cancer, inflammatory and cardiac diseases are commonly associated with long-term increased production and release of reactive oxygen species referred to as oxidative stress.
Friederike Cuello +4 more
doaj +1 more source
Drosophila cAMP-dependent protein kinase.
cAMP-dependent protein kinase has been purified to homogeneity from adult bodies of Drosophila melanogaster. It is tetrameric in structure with two regulatory and two catalytic subunits that dissociate when activated by cAMP. The regulatory subunit exists in phospho and dephospho forms, which have electrophoretic mobilities in sodium dodecyl sulfate ...
J L, Foster +3 more
openaire +2 more sources
A protein of apparent Mr = 15,000 on sodium dodecyl sulfate-polyacrylamide gel electrophoresis is the major plasma membrane substrate for cAMP-dependent protein kinase (PK-A) and protein kinase C (PK-C) in several different tissues. In the work described
Cathy J. Palmer, B. Scott, L. R. Jones
semanticscholar +1 more source
Receptor for activated C kinase-1 facilitates protein kinase C-dependent phosphorylation and functional modulation of GABA(A) receptors with the activation of G-protein-coupled receptors [PDF]
GABA(A) receptors are the principal sites of fast synaptic inhibition in the brain. These receptors are hetero-pentamers that can be assembled from a number of subunit classes: alpha(1-6), beta(1-3), gamma(1-3), delta(1), epsilon, theta, and pi, but the ...
Trevor G Smart +7 more
core
Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors. [PDF]
GABAA receptors are important for inhibition in the CNS where neurosteroids and protein kinases are potent endogenous modulators. Acting individually, these can either enhance or depress receptor function, dependent upon the type of neurosteroid or ...
Adams, JM +5 more
core +1 more source

