Results 41 to 50 of about 1,906,035 (244)

A family of cAMP-binding proteins that directly activate Rap1.

Science, 1998
cAMP (3',5' cyclic adenosine monophosphate) is a second messenger that in eukaryotic cells induces physiological responses ranging from growth, differentiation, and gene expression to secretion and neurotransmission.
H. Kawasaki, G. Springett, N. Mochizuki, S. Toki, M. Nakaya, M. Matsuda, D. Housman, A. Graybiel   +7 more
semanticscholar   +1 more source

«The shameful proposal to return to the motherland…»: declaring bolshevik diplomacy of amnesty in the camp of interned soldiers-ukrainians Kalisz, Poland (1922)

Європейські історичні студії, 2018
The article reproduces events, which took place on the eve of and during the announcement by the Polish-Soviet delegation of two amnesties in the camp of interned Ukrainian soldiers Kalisz (Poland) in 1922.
Іhor Sribnyak
doaj   +1 more source

The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways

Journal of Inflammation Research, 2021
Xinwei Cao,1 Yajun Li,1 Jianrong Shi,2 Huifang Tang1 1Department of Pharmacology, School of Basic Medical Sciences, Zhejiang University, Hangzhou, 310058, People’s Republic of China; 2Department of Clinical Laboratory, Children’s Hospital ...
Cao X, Li Y, Shi J, Tang H
doaj  

СПРИЙНЯТТЯ ОДНЕ ОДНОГО В КОНТЕКСТІ СТАНОВЛЕННЯ ОСОБИСТОСТІ. ПРОБЛЕМНЕ ДОСЛІДЖЕННЯ / PERCEPTION OF ONE ANOTHER IN THE CONSTRUCTION OF THE SELF. CASE STUDY

Актуальні питання суспільних наук та історії медицини, 2017
Анотація. У статті розглядається, як мова будує художню і етнічну ідентичність рік до, під час і після досвіду концтаборів, в книзі автобіографічного змісту Аарона Аппельфельдта «Історія життя». Мови його дитинства: німецька (рідна мова), ідиш (мова його
Кармен Деребуш
doaj   +1 more source

Shockwaves Suppress Adipocyte Differentiation via Decrease in PPARγ

Cells, 2020
Adipogenesis is a crucial cellular process that contributes to the expansion of adipose tissue in obesity. Shockwaves are mechanical stimuli that transmit signals to cause biological responses.
Wonkyoung Cho, SeoYeon Kim, Myeongsook Jeong, Young Mi Park   +3 more
doaj   +1 more source

Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging

Scientific Reports, 2017
cAMP is a common second messenger that is involved in various physiological processes. To expand the colour palette of available cAMP indicators, we developed a red cAMP indicator named “Pink Flamindo” (Pink Fluorescent cAMP indicator).
Kazuki Harada, Motoki Ito, Xiaowen Wang, Mika Tanaka, Devina Wongso, Ayumu Konno, H. Hirai, H. Hirase, T. Tsuboi, T. Kitaguchi   +9 more
semanticscholar   +1 more source

Use of a randomized clinical trial design to study cognitive rehabilitation approaches to enhance warfighter performance

Contemporary Clinical Trials Communications, 2020
Within the military, cognitive readiness is essential to ensure the warfighter can return to highly demanding combat training and deployment operations.
Ida Babakhanyan, Melissa Jensen, Rosemay A. Remigio-Baker, Paul Sargent, Jason M. Bailie   +4 more
doaj  

Un automne à PinceventLe campement magdalénien du niveau IV20

Les Nouvelles de l’Archéologie, 2015
Since 1964, when the Magdalenian site of Pincevent was discovered by A. Leroi-Gourhan and his team, the methods of excavation and analysis have evolved.
Michèle Julien, Claudine Karlin
doaj   +1 more source

Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells – Role of Anchored Protein Kinase A Signaling Units

Frontiers in Immunology, 2016
The cyclic AMP/protein kinase A (cAMP/PKA) pathway is one of the most common and versatile signal pathways in eukaryotic cells. A-kinase anchoring proteins (AKAPs) target PKA to specific substrates and distinct subcellular compartments providing spatial ...
Vanessa L. Wehbi, K. Taskén
semanticscholar   +1 more source

Fourth-Generation Epac-Based FRET Sensors for cAMP Feature Exceptional Brightness, Photostability and Dynamic Range: Characterization of Dedicated Sensors for FLIM, for Ratiometry and with High Affinity

PLoS ONE, 2015
Epac-based FRET sensors have been widely used for the detection of cAMP concentrations in living cells. Originally developed by us as well as others, we have since then reported several important optimizations that make these sensors favourite among many
J. Klarenbeek, J. Goedhart, A. V. van Batenburg, Daniella Groenewald, K. Jalink   +4 more
semanticscholar   +1 more source