Results 121 to 130 of about 42,673 (234)

Molecular and cellular effects of the combined treatment with Camptothecin and Roscovitine in human lung and colon adenocarcinoma cells [PDF]

, 2008
De Mattia, Roberta
core   +1 more source

High-Precision Field- Effect Transistor Biosensor for Analyzing Differential Effects of Anti-Cancer Drugs on Cancerous and Non-Cancerous Cells

Biosensors
A high-precision biosensor technique is introduced, offering the capability to independently evaluate the effects of anti-cancer drugs on both cancerous (RAJI) and non-cancerous (WIL2S) cells.
Can Li, Can Hu, Ling Li, Feng He, Xiaofei Li   +4 more
doaj   +1 more source

Camptothecin: A promising antiretroviral drug

Journal of Biomedical Science, 1996
The plant alkaloid camptothecin (CPT) has demonstrated the ability to inhibit replication of the equine anemia virus (E1AV) and the human immunodeficiency virus (HIV) in infected cells in culture. Further, CPT prevented the development of lymphoma and erythroleukemia in mice infected with the Moloney murine leukemia virus and the Friend erythroleukemia
openaire   +2 more sources

Layered double hydroxides-indomethacin nanohybrids: intercalation, pH influence, stability and release properties [PDF]

, 2016
In this work, three pH values (8, 9 and 10) were studied for the insertion of Indomethacin (Indo) molecules into Layered Double Hydroxides (LDHs). The obtained results showed that the LDH materials have been a good storage for the drug.
Crivello, Mónica Elsie, Granero, Gladys Ester, Longhi, Marcela Raquel, Mendieta, Silvia Nazaret, Oliva, Marcos Iván, Perez, Celso Francisco, Reyes Nuñez, Patricio   +6 more
core   +1 more source

Future-Oriented Nanosystems Composed of Polyamidoamine Dendrimer and Biodegradable Polymers as an Anticancer Drug Carrier for Potential Targeted Treatment

Pharmaceutics
Background/Objectives: Camptothecin (CPT) is a well-known chemical compound recognized for its significant anticancer properties. However, its clinical application remains limited due to challenges related to CPT’s high hydrophobicity and the instability
Katarzyna Strzelecka, Adam Kasiński, Tadeusz Biela, Anita Bocho-Janiszewska, Anna Laskowska, Łukasz Szeleszczuk, Maciej Gawlak, Marcin Sobczak, Ewa Oledzka   +8 more
doaj   +1 more source

Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay. [PDF]

EMBO Mol Med
Hough SH, Jhujh SS, Awwad SW, Lewis OE, Lam S, Thomas JC, Mosler T, Bader A, Bartik L, McKee S, Amudhavalli S, Colin E, Damseh N, Clement E, Cacheiro P, Majumdar A, Smedley D, Fluss J, Giannini R, Thiffault I, Zagnoli Vieira G, Belotserkovskaya R, Smerdon SJ, Beli P, Galanty Y, Carnie CJ, Stewart GS, Jackson SP.   +27 more
europepmc   +2 more sources

Generation of NBS1 knockout in Chinese hamster cells revealed ATR role for radiation and etoposide induced DNA damage in absence of NBS1 proteins. [PDF]

Front Oncol
Badakul G, Maeda J, Kato TA.
europepmc   +1 more source

Antiproliferative Effect of Okra Seed Protein Isolate against HepG2 and A549 Cell Lines. [PDF]

Chem Biodivers
Maistry L, Gerrano AS, Mellem JJ.
europepmc   +1 more source

Camptothecin-PHA nanoparticles attenuate drug-induced gut microbiome dysbiosis and metabolic toxicity. [PDF]

Front Microbiol
Liu S, Rao B, Liu W, Wang X, Wang H, Liu L, Zhang G, Sun J, Li L, Wei D, Yu Z, Ren Z.   +11 more
europepmc   +1 more source

Mechanistic role of CD82 palmitoylation in augmenting antitumor drug sensitivity via apoptosis regulation. [PDF]

Front Oncol
Li L, Yu Y, Chen S, Zhang Y, Zhang C, Yao X, Xu H, Wu S, Gong X, Han W, Zhang Y, Li Y.   +11 more
europepmc   +1 more source