Results 111 to 120 of about 39,854 (281)

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, Volume 13, Issue 33, 15 June 2026.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Camptothecin türevlerinin sentezi

, 2005
This study presents synthetic studies on camptothecin, a potent antitumor agent in order to improve its stability and solubility without reducing its activity.
Duygu, Arife Neşe
core  

M-polynomial and NM-polynomial indices of camptothecin–polymer conjugate IT-101 structure

Main Group Metal Chemistry
Camptothecin is a naturally occurring alkaloid known for its significant and selective inhibition of the topoisomerase nuclear enzyme, a critical target in cancer treatment.
Teng Ling, Zhang Lei, Abbas Muhammad Mohsin, Naeem Muhammad, Tchier Fairouz, Wang Yong   +5 more
doaj   +1 more source

Camptothecin-Loaded and Manganese Dioxide-Coated Polydopamine Nanomedicine Used for Magnetic Resonance Imaging Diagnosis and Chemo-Photothermal Therapy for Lung Cancer

International Journal of Nanomedicine, 2022
Mingliang Su,* Yukun Chen,* Lijun Jia, Zhanxia Zhang Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, People’s Republic of China*These authors contributed equally to this ...
Su M, Chen Y, Jia L, Zhang Z
doaj  

Light‐Controlled Peptide Self‐Assembly: From Physicochemical Principles to Emerging Biomedical Applications

Aggregate, Volume 7, Issue 6, June 2026.
This review surveys recent advances in light‐controlled peptide self‐assembly for the design of smart soft matter. It summarizes the underlying physicochemical principles, including thermodynamic control for reshaping free‐energy landscapes, and nonequilibrium control to produce kinetically trapped states and dissipative structures.
Lidong Chen, Yanan Cui, Yuxuan Han, Chuqiang Ke, Wendi Jiang, Rui Yu, Lingling Kang, Kai Liu   +7 more
wiley   +1 more source

Integrating antibody–drug conjugates into solid tumor oncology: Current standards and future directions

Cancer, Volume 132, Issue S1, 1 June 2026.
Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho, Joana Albuquerque, Andreia Lopes, Emiliano Calvo   +3 more
wiley   +1 more source

Mechanisms of Camptothecin Resistance by Human Topoisomerase I Mutations

, 2004
International audienceHuman topoisomerase I relaxes superhelical tension associated with DNA replication, transcription and recombination by reversibly nicking one strand of duplex DNA and forming a covalent 3'-phosphotyrosine linkage. This enzyme is the
Burgin, Alex, Chrencik, Jill, Staker, Bart, Redinbo, Matthew, Pommier, Yves, Stewart, Lance, Pourquier, Philippe   +6 more
core   +1 more source

In Silico Study of Camptothecin-Based Pro-Drugs Binding to Human Carboxylesterase 2

Biomolecules
Pro-drugs, which ideally release their active compound only at the site of action, i.e., in a cancer cell, are a promising approach towards an increased specificity and hence reduced side effects in chemotherapy.
Frank Beierlein, Anselm H. C. Horn, Heinrich Sticht, Andriy Mokhir, Petra Imhof   +4 more
doaj   +1 more source

Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel

Nature Biomedical Engineering, 2020
Feihu Wang, Hao Su, Dongqing Xu, Wenbing Dai, Weijie Zhang, Zongyuan Wang, Caleb F. Anderson, Mengzhen Zheng, Richard Oh, F. Wan, H. Cui   +10 more
semanticscholar   +1 more source

Current advances in liposome–extracellular vesicle hybrid systems for cancer drug delivery

Clinical and Translational Discovery, Volume 6, Issue 3, June 2026.
Liposome–extracellular vesicle hybrids combine synthetic stability with biological targeting capability. Hybrid nanovesicles enhance drug loading efficiency and tumour‐specific delivery. Advanced fusion strategies improve membrane integration and functional preservation.
Arina Habibi, Mohana Sakhti, Touraj Ahmadi Jouybari, Parnian Yavari, Reza Mozafari, Gelavizh Rostaminasab, Shima Rahmati   +6 more
wiley   +1 more source