Results 131 to 140 of about 39,854 (281)
Comparative cytotoxicity of camptothecin against MPC and MTT cells.
, 2014 Parallel tests of camptothecin toxicity on MPC and MTT cell lines at two time points, demonstrate greater sensitivity of the more aggressive MTT line to low camptothecin concentrations.
Alessio Giubellino (283359) +5 more
core +1 more source
Boron‐10 carriers and their applications in boron neutron capture therapy
Precision Radiation Oncology, Volume 10, Issue 2, Page 205-241, June 2026.Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang +7 more
wiley +1 more source
Delta133p53ß protects cancer cells from camptothecin-induced apoptosis.
, 2017 (a) Apoptosis assay showing the sensitivity to 5μM camptothecin of mock-transfected (control) SW620 cells and after transfection with siRNAs against RhoB.
Pierre Roux (121774) +9 more
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Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications
Small, Volume 22, Issue 33, 12 June 2026.Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito +2 more
wiley +1 more source
Gene size is a major contributing factor to the effects of camptothecin on RNA synthesis.
, 2013 Human fibroblasts were treated with 20 µM camptothecin for 45 min with 2 mM Bru added during the last 15 min of camptothecin treatment to label nascent RNA followed by Bru-Seq.
Benjamin Biewen (476021) +9 more
core +1 more source
Enhancing CRISPR/Cas‐Mediated Gene Knockout With Short Non‐Homologous Oligonucleotides
Plant Biotechnology Journal, Volume 24, Issue 6, Page 3742-3753, June 2026.ABSTRACT Chlamydomonas reinhardtii is a model green microalga that has great industrial potential as a sustainable bio‐factory for recombinant protein and high‐value chemical production. Efficient genome editing tools are required to redesign this organism for synthetic biology applications. CRISPR‐Cas editing technologies have already been adapted for
Yen Peng Chew +7 more
wiley +1 more source
Camptothecin: A promising antiretroviral drug
Journal of Biomedical Science, 1996 The plant alkaloid camptothecin (CPT) has demonstrated the ability to inhibit replication of the equine anemia virus (E1AV) and the human immunodeficiency virus (HIV) in infected cells in culture. Further, CPT prevented the development of lymphoma and erythroleukemia in mice infected with the Moloney murine leukemia virus and the Friend erythroleukemia
openaire +2 more sources
Effect of camptothecin on transcriptional readthrough and synthesis of PROMPTs and eRNA.
, 2013 As in Figure 1, human fibroblasts were treated with 20 µM camptothecin for 45 min with 2 mM Bru added during the last 15 min of camptothecin treatment to label nascent RNA followed by Bru-Seq.
Benjamin Biewen (476021) +9 more
core +1 more source
BiosensorsA high-precision biosensor technique is introduced, offering the capability to independently evaluate the effects of anti-cancer drugs on both cancerous (RAJI) and non-cancerous (WIL2S) cells.
Can Li +4 more
doaj +1 more source
, 2013 Camptothecin (CPT), the third largest anticancer drug, is produced mainly by Camptotheca acuminata and Nothapodytes foetida. CPT itself is the starting material for clinical CPT-type drugs, but the plant-derived CPT cannot support the heavy demand from ...
Pu, X +5 more
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