Results 141 to 150 of about 301 (159)

Expression of a Canavalia brasiliensis Lectin (ConBr) Precursor in Pichia pastoris

Protein & Peptide Letters, 2008
A precursor of ConBr, a glucose/mannose-binding plant lectin, was expressed in the yeast Pichia pastoris. Western blot analysis of transformed cells detected an intracellularly recombinant protein band with ca. 34.5 kDa. The recombinant protein was apparently active as suggested by its strong interaction with the mannose-rich yeast cell debris.
C P S, Carvalho, C S, Rocha, D R, Nepomuceno, J T A, Oliveira, T B, Grangeiro   +4 more
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Renal Effects Of The Lectin From Canavalia Brasiliensis Seeds

Protein & Peptide Letters, 2001
The lectin from the seeds of Canavalia brasiliensis (Con Br) was tested for its renal effects using the isolated perfusion rat kidney method. Three different doses were examined (3,10 and 30 microgram / ml), which were compared with a control group. The control group was perfused with only Krebs-Henseleit solution containing 6 percent BSA.
Edson Teixeira, Alexandre Havt, Paulo Barbosa, Dalgimar Meneses, Manasses Fonteles, Helena Monteiro, Alexander Sampaio, Benildo Cavada   +7 more
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Antidepressant‐like effect of lectin from Canavalia brasiliensis (ConBr) administered centrally in mice

Pharmacology Biochemistry and Behavior, 2006
This study investigates the action of the central administration of the lectins isolated from Canavalia brasiliensis seeds (ConBr) and from Canavalia ensiformes seeds, (Concanavalin A, ConA) in the forced swimming test (FST) in mice. ConBr (1-10 micro g/site, i.c.v.), but not ConA, produced a decrease in the immobility time in the FST (observed at the ...
Manuella P Kaster, Francesca Rossi, Edson Holanda Teixeira   +2 more
exaly   +3 more sources

The Lectin Content of Cotyledonary Callus from Canavalia brasiliensis (Mart. ex. Benth)

Asian Journal of Plant Sciences, 2005
Fabia M.B. Da Si, Renato A. Moreira ., Ana C.G. Horta ., Andre Luis C. Silva .   +3 more
exaly   +2 more sources

Antidepressant-like effect of Canavalia brasiliensis (ConBr) lectin in mice: Evidence for the involvement of the glutamatergic system

Pharmacology Biochemistry and Behavior, 2014
Lectins recognize and reversibly bind to carbohydrates attached to proteins and lipids modulating a variety of signaling pathways. We previously showed that ConBr, a lectin from Canavalia brasiliensis seeds, produced an antidepressant-like effect in mice by modulating the monoaminergic neurotransmitter systems.
Débora K. Rieger, Ana Paula Costa, Josiane Budni, Morgana Moretti, Sabrina Giovana Rocha Barbosa, Kyria S. Nascimento, Edson H. Teixeira, Benildo S. Cavada, Ana Lúcia S. Rodrigues, Rodrigo B. Leal   +9 more
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Comparison of immunomodulatory properties of mannose-binding lectins from Canavalia brasiliensis and Cratylia argentea in a mice model of Salmonella infection

International Immunopharmacology, 2016
The immunomodulatory properties of mannose-binding lectins ConBr (Canavalia brasiliensis) and CFL (Cratylia argentea) were investigated comparatively in a model of Salmonella infection. The lectins were intraperitoneally (i.p.) administered to mice daily for three days before the bacterial challenge with Salmonella enterica Ser. Typhimurium (0.2 mL i.p.
Ayrles F B Silva, Marcio V Ramos, JOSÉ Vitor Lima-Filho   +2 more
exaly   +3 more sources

Opioid‐like antinociceptive effects of oral administration of a lectin purified from the seeds ofCanavalia brasiliensis

Fundamental & Clinical Pharmacology, 2011
AbstractThe objective of this study was to evaluate the antinociceptive effects of a lectin fromCanavalia brasiliensis(ConBr) when administered orally to murine models of chemical and thermal nociception. ConBr up to 100 mg/kg produced significant and dose‐dependent antinociceptive effects: 81% reduction in abdominal writhing induced by 0.6% acetic ...
Alana, de Freitas Pires, Ana Maria Sampaio, Assreuy, Érika Augusta Batista, Lopes, Natália Rocha, Celedônio, Carlos Eduardo Alves, Soares, Natália Velloso Fontenelle Camelo, Rodrigues, Paloma Leão, Sousa, Raquel Guimarães, Benevides, Celso Shiniti, Nagano, Benildo Sousa, Cavada, José Henrique, Leal-Cardoso, Andrelina Noronha, Coelho-de-Souza, Cláudia Ferreira, Santos   +12 more
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ConBr, a Lectin from Canavalia brasiliensis Seeds, Protects Against Quinolinic Acid-Induced Seizures in Mice

Neurochemical Research, 2011
Lectins are proteins capable of reversible binding to carbohydrates or glycoconjugates. In the central nervous system of mammals, lectins with affinity for mannose/glucose or galactose can modulate cellular communication. ConBr, a lectin isolated from the seeds of Canavalia brasiliensis, previously showed antidepressant effect in the forced swimming ...
Michael A, Russi, Samuel, Vandresen-Filho, Débora K, Rieger, Ana Paula, Costa, Mark W, Lopes, Rodrigo M S, Cunha, Edson H, Teixeira, Kyria S, Nascimento, Benildo S, Cavada, Carla I, Tasca, Rodrigo B, Leal   +10 more
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Partitioning and recovery of Canavalia brasiliensis lectin by aqueous two-phase systems using design of experiments methodology

Separation and Purification Technology, 2010
The performance of aqueous two-phase systems (ATPS) composed by poly(ethylene glycol) (PEG)- and different salts (sodium citrate, potassium phosphate, sodium sulfate and ammonium sulfate) has been evaluated and compared for the selective isolation of Canavalia brasilienses lectin (ConBr) from crude extracts of C. brasilienses seeds.
Kelany S. Nascimento, P.A.J. Rosa, K.S. Nascimento, B.S. Cavada, A.M. Azevedo, M.R. Aires-Barros   +5 more
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SAM of Gliotoxin on Gold: A Natural Product Platform for Sugar Recognition based on the Immobilization of Canavalia brasiliensis lectin (ConBr)

Electrochimica Acta, 2017
Abstract We report the successful fabrication of a novel gold surface coated with a thiol-lectin multilayer that showed specific interaction towards D-mannose sugars. Firstly, the gold surface was spontaneously modified with gliotoxin (gtx), a sulfur containing diketopiperazine isolated from marine-derived fungus, and fully characterized by ...
Dieric S. Abreu, Ticyano P. Sousa, Caio B. Castro, Mayara N.V. Sousa, Thiago T. Silva, Francisco W.Q. Almeida-Neto, Marcos V.A. Queiros, Bárbara S.F. Rodrigues, Maria C.F. Oliveira, Tércio F. Paulo, Benildo S. Cavada, Kyria S. Nascimento, Marcia L.A. Temperini, Izaura C.N. Diógenes   +13 more
openaire   +1 more source