Synthesis of nine safrole derivatives and their antiproliferative activity towards human cancer cells [PDF]
, 2010 Indexación: ScieloSafrole from sassafras oil (Ocoteapretiosa Mez., Lauraceae), is an abundant natural product showing interesting functionality and chemical structure.
Carrasco Altamirano, Héctor +5 more
core +2 more sources
Use of recurrence quantification analysis to examine associations between changes in text structure across an expressive writing intervention and reductions in distress symptoms in women wth breast cancer [PDF]
, 2019 The current study presents an exploratory analysis of using Recurrence Quantification Analysis (RQA) to analyze text data from an Expressive Writing Intervention (EWI) for Danish women treated for Breast Cancer.
Bovbjerg, D. +5 more
core +1 more source
Early differential responses elicited by BRAFV600E in adult mouse models
Cell Death and Disease, 2022 The BRAF gene is frequently mutated in cancer. The most common genetic mutation is a single nucleotide transition which gives rise to a constitutively active BRAF kinase (BRAFV600E) which in turn sustains continuous cell proliferation.
Giuseppe Bosso +5 more
doaj +1 more source
The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer [PDF]
, 2015 RNA-binding proteins (RBPs) are increasingly identified as post-transcriptional drivers of cancer progression. The RBP LARP1 is an mRNA stability regulator, and elevated expression of the protein in hepatocellular and lung cancers is correlated with ...
Blagden, S +3 more
core +1 more source
Update Breast Cancer 2020 Part 3 – Early Breast Cancer [PDF]
Geburtshilfe und Frauenheilkunde, 2020 AbstractThe treatment of patients with early breast cancer has always been characterised by escalation by new therapies and de-escalation through identification of better treatment regimens or introduction of better tools to estimate prognosis. Efforts in some of these areas in the last few years have led to solid data. The results of the large studies
Huober, Jens +18 more
openaire +2 more sources
A Phase I Study of Abiraterone Acetate Combined with BEZ235, a Dual PI3K/mTOR Inhibitor, in Metastatic Castration Resistant Prostate Cancer. [PDF]
, 2017 Lessons learnedThe combination of standard dose abiraterone acetate and BEZ235, a pan-class I PI3K and mTORC1/2 inhibitor, was poorly tolerated in men with progressive mCRPC.Although the clinical development of BEZ235 has been discontinued in prostate ...
Friedlander, Terence +6 more
core +1 more source
HeliyonBackground: The incidence of malignancy and cardiovascular disease (CVD) is increasing worldwide. However, it is not entirely clear how the coexistence of CVD at the time of cancer diagnosis affects the overall survival of patients with cancer.
Yoshihiro Kuwabara +8 more
doaj +1 more source
The Influence of Patient Exposure to Breast Reconstruction Approaches and Education on Patient Choices in Breast Cancer Treatment. [PDF]
, 2019 BackgroundThe landscape of surgical and medical management and patient choices for breast cancer treatment changes as breast reconstruction and oncoplastic approaches improve and diversify.
Blair, Sarah L +4 more
core
BJS Open, 2020 Background Pancreatoduodenectomy (PD) with portal vein resection (PVR) is a standard operation for pancreatic ductal adenocarcinoma (PDAC) with portal vein (PV) invasion, but positive margin rates remain high.
A. Oba +7 more
doaj +1 more source
The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer [PDF]
, 2010 <b>Background & aims:</b> The involvement of a systemic inflammatory response, as evidenced by the Glasgow Prognostic Score (GPS), is associated with weight loss and poor outcome in patients with non-small cell lung cancer.
Forrest, L.M. +3 more
core +1 more source