Results 91 to 100 of about 3,021,316 (188)

Cytotoxic Activity of Hyptis Pectinate Extracts on MCF-7 Human Breast Cancer Cells [PDF]

, 2020
Hyptis pectinata (L.) poit, popularly known in the world as “comb bushmint” is a medicinal plant commonly used for the treatment of throat and skin inflammations, bacterial infection, pain and cancer.
Cahyono, Bambang, Suzery, Meiny, Amalina, Nur Dina   +2 more
core   +1 more source

Cell-Free DNA Plasma Levels Differ in Age-Specific Pattern in Healthy Rats and Castrates with Testosterone-Induced Benign Prostatic Hyperplasia

International Journal of Genomics, 2019
The purpose of this work was to study changes in the level of cell-free DNA (cfDNA) in the blood of young and old rats in the normal state and with induced benign prostatic hyperplasia (BPH).
I. N. Vasilyeva, V. G. Bespalov, J. D. Von, A. L. Semenov, G. V. Tochilnikov, V. A. Romanov, I. K. Alvovsky, D. A. Baranenko   +7 more
doaj   +1 more source

Bioactive Peptides From the Cucurbitaceae Family: From Identification and Health‐Promoting Functions to Industrial Utilization

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
From fruit to function: Cucurbitaceae‐derived peptide production, bioactive potential screening and industrial applications. ABSTRACT Cucurbitaceae is a major plant family within the kingdom Plantae, encompassing popular food crops such as zucchini, squash, pumpkins, and melons.
Himani R. Kekiri Obada Gamage, Mahya Bahmani, Utpal Bose, Mekhala Vithana, Michelle L. Colgrave, Angéla Juhász   +5 more
wiley   +1 more source

Sclareol Inhibit Cell Growth and Induces Apoptosis via Activation of p53/p21 Signaling Pathways in Human Oral Squamous Cell Carcinoma Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The Schematic representation of the possible molecular mechanism of sclareol induces apoptosis through p53 and p21‐associated signaling in KB cells. ABSTRACT One of the most common prevalent forms of cancer in the world is oral squamous cell carcinoma (OSCC).
Anandhi Nallu, Suresh Kathiresan, Theerthu Azhamuthu, Hemavardhani Ramadoss, Nihal Ahamed Abulkalam Asath, Pugazhendhi Ravichandran, Rajeswari Vasu   +6 more
wiley   +1 more source

CAR-T Cell Therapy: Revolutionizing Cancer Treatment [PDF]

CAR-T cell therapy has emerged as a groundbreaking approach in cancer treatment, offering new hope for patients with refractory and relapsed malignancies.
Sayh, Melad, Eskandar, Kirolos
core   +2 more sources

The Combination of Sorafenib and PGV-1 Inhibits the Proliferation of Hepatocellular Carcinoma Through c-Myc Suppression in an Additive Manner: In Vitro Studies

Advances in Pharmacological and Pharmaceutical Sciences
Hepatocellular carcinoma (HCC) is one of the most aggressive types of liver cancer, and it is frequently associated with upregulated c-Myc expression.
Dhania Novitasari, Ikuko Nakamae, Noriko Yoneda-Kato, Jun-ya Kato, Yoshitaka Hippo, Yusuke Suenaga, Dyaningtyas Dewi Pamungkas Putri, Edy Meiyanto, Muthi’ Ikawati   +8 more
doaj   +1 more source

Downregulation of KCTD12 contributes to melanoma stemness by modulating CD271

Cancer Biology & Medicine, 2019
Objective Cancer metastasis remains the primary cause of cancer-related death worldwide. In a previous study, we found that levels of BTB/POZ domain-containing protein KCTD12 are lower in metastatic melanoma cells than in parental melanoma cells.
Weiyu Shen, Yumei Li, Bifei Li, Liping Zheng, Xiaodong Xie, Jingqing Le, Yusheng Lu, Tao Li, Fan Chen, Lee Jia   +9 more
doaj   +1 more source

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

Molecular Carcinogenesis, Volume 65, Issue 9, Page 1052-1062, September 2026.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh, Eun‐Ryeong Hahm, Bruce L. Jacobs, Shivendra V. Singh   +3 more
wiley   +1 more source

Statistical considerations of chemoprevention clinical trials in prostate cancer

, 1999
The design and analysis of chemoprevention trials in prostate cancer is more complicated than that of an ordinary treatment efficacy trial. The following issues must be taken into account when designing prospective randomized chemoprevention trials: (1 ...
Symposium on Strategies for the Chemoprevention of Prostate Cancer, Collette, Laurence, Sylvester, Richard J.   +2 more
core   +1 more source

A drug-repurposing nanotheranostic for synergistic management of resistant bacterial pneumonia

Asian Journal of Pharmaceutical Sciences
The rising threat of antibiotic resistance severely compromises the treatment of bacterial pneumonia, underscoring the urgent need for innovative and comprehensive therapeutic strategies.
Xianbin Sun, Xinyi Wang, Fangying Zheng, Ruofei Xu, Xinyi Shen, Ding Tan, Xudong Li, Ya Wang, Kaiming Peng, Haijun Chen, Xiumei Li, Yu Gao   +11 more
doaj   +1 more source