Results 151 to 160 of about 85,373 (307)
Cancro da mama hereditário: dupla heterozigotia para variantes patogénicas nos genes BRCA1 e ATM [PDF]
, 2019 Introdução/objetivos: O cancro da mama hereditário (CMH) representa 5-10% dos casos de cancro da mama, destes ~30% devem-se a variantes patogénicas germinativas nos genes BRCA1 e BRCA2.
Carreiro, Helena +7 more
core
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Variabilidade No Tratamento Do Cancer De Mama No Brasil [PDF]
Value in Health, 2013 Cherchiglia, M. L. +5 more
openaire +2 more sources
Clinical and Biomedical Research, 2012 Introdução: Foram publicados na Revista Brasileira de Mastologia dados importantes sobre a população feminina de Xangri-Lá/RS, demonstrando alta incidência de câncer de mama.
Nilton Leite Xavier +2 more
doaj
Construction and validity of a storyboard about breast cancer for women deprived of liberty. [PDF]
Rev Bras Enferm, 2023 Galiza DDF +3 more
europepmc +1 more source
Study of influence of regulatory polymorphisms of expression in development of breast cancer [PDF]
, 2013 The human genome has millions of genetics variants that can affect gene expression. These variants are known as cis-regulatory variants and are responsible for intra-species phenotypic differences and individual susceptibility to disease.
Lopes, Joana Margarida Teixeira
core
The C‐Terminal Regions of TRAK Proteins Contain MIRO‐Independent Mitochondrial Localization Domains
Cytoskeleton, EarlyView.ABSTRACT Current models suggest that MIRO GTPases anchor cytoskeletal motors to the mitochondrial outer membrane (MOM). However, our previous findings indicate that the unconventional myosin, MYO19, interacts with MIRO weakly and that a MIRO‐independent MOM‐localizing domain interacts more tightly with the MOM.
Lili Mitchell +4 more
wiley +1 more source
[Cognitive deficits with chemotherapy in women with breast cancer: a bibliographic revisión] [PDF]
Rev Fac Cien Med Univ Nac Cordoba, 2023 Arce B, Grañana N.
europepmc +1 more source
A Computational Workflow for Cell Line Profiling by Imaging Mass Cytometry
Cytometry Part A, EarlyView.ABSTRACT In single‐cell spatial phenotyping biology, imaging mass cytometry (IMC) stands out as a cutting‐edge, highly multiplexed technology driving discoveries across various disease areas. In vitro profiling relies on tumor‐derived cancer cell lines, known for their diverse morphologies and phenotypes.
Alexandre Bouzekri +2 more
wiley +1 more source
FlexMat, EarlyView.The development of conventional phototheranostic nanomedicines suffers from an intrinsic trade‐off between NIR‐II fluorescence emission and phototherapeutic effects, leading to poor overall efficacy. Herein, we propose an innovative fluorination strategy by constructing fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents to ...
Xiaoming Hu +7 more
wiley +1 more source