Results 21 to 30 of about 411,149 (312)
Recent Progress in Dendritic Cell-Based Cancer Immunotherapy
, 2021 Cancer immunotherapy aims to treat cancer by enhancing cancer-specific host immune responses. Recently, cancer immunotherapy has been attracting much attention because of the successful clinical application of immune checkpoint inhibitors targeting the ...
Kazuhiko Matsuo +5 more
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Transcription factors in fibroblast plasticity and CAF heterogeneity
Journal of Experimental & Clinical Cancer Research, 2023 In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro ...
Roberta Melchionna +4 more
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Recent Advances in Molecular Mechanisms of Cancer Immunotherapy
, 2023 Cancer is among the current leading causes of death worldwide, despite the novel advances that have been made toward its treatment, it is still considered a major public health concern.
Muhammad Omer Iqbal +7 more
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Escape from immunotherapy: possible mechanisms that influence tumor regression/progression [PDF]
, 2004 Tumor escape is one major obstacle that has to be addressed prior to designing and delivering successful immunotherapy. There is compelling evidence to support the notion that immunogenic tumors, in murine models and cancer patients, can be rejected by ...
Ahmad, M, Ali, SA, Rees, RC
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Developments in Cancer Immunotherapy [PDF]
Digestive Diseases, 2010 Significant advances have been made in the field of cancer immunology and immunotherapy over the last three decades. An important step forward was the identification of human cancer antigens eliciting spontaneous immune responses in cancer patients. The most immunogenic human cancer antigens known to date belong to the cancer-testis family of antigens,
van den Broek, M +2 more
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, 2020 In the last few decades, cancer immunotherapy becomes an important tactic for cancer treatment. However, some immunotherapy shows certain limitations including poor therapeutic targeting and unwanted side effects that hinder its use in clinics. Recently,
Tilahun Ayane Debele +2 more
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Molecular Oncology, 1999 The remarkable specificity of the immune system through antigen recognition has long attracted investigators to the possibility of immune‐based therapy for cancer. Previous cancer immunotherapeutics had been restricted to non‐specific immunomodulatory agents, such as the cytokines IL‐2 or IFN‐α.
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Immunotherapy through the Lens of Non-Small Cell Lung Cancer
, 2023 Immunotherapy has revolutionised anti-cancer treatment in solid organ malignancies. Specifically, the discovery of CTLA-4 followed by PD-1 in the early 2000s led to the practice-changing clinical development of immune checkpoint inhibitors (ICI ...
Saoirse Flanagan +5 more
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, 2021 Cancer immunotherapy harnesses the immune system by targeting tumor cells that express antigens recognized by immune system cells, thus leading to tumor rejection.
Narges Baluch +19 more
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Cancer Immunotherapy: Where Next?
, 2023 The fundamental problem of dealing with cancer is that cancer cells are so like normal cells that it is very hard to find differences that can be a basis for treatment without severe side effects.
Walter Bodmer, Vita Golubovskaya
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