Results 31 to 40 of about 3,394,140 (306)

Advancing Cancer Immunotherapy: From Molecular Mechanisms to Clinical Applications

, 2023
In recent years, cancer immunotherapy research has made remarkable progress, completely transforming the cancer treatment landscape [...
Timothy Starr, Subbaya Subramanian, Xianda Zhao   +2 more
core   +1 more source

Immunotherapy of cancer [PDF]

European Journal of Pharmacology, 2009
Major advances have been made in the field of immunology in the past two decades. A better understanding of the molecular and cellular mechanisms controlling the immune system has opened the door to many innovative and promising new cancer therapies that manipulate the immune response.
Hossein, Borghaei, Mitchell R, Smith, Kerry S, Campbell   +2 more
openaire   +2 more sources

Transcription factors in fibroblast plasticity and CAF heterogeneity

Journal of Experimental & Clinical Cancer Research, 2023
In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro ...
Roberta Melchionna, Paola Trono, Anna Di Carlo, Francesca Di Modugno, Paola Nisticò   +4 more
doaj   +1 more source

Recent Advances in Molecular Mechanisms of Cancer Immunotherapy

, 2023
Cancer is among the current leading causes of death worldwide, despite the novel advances that have been made toward its treatment, it is still considered a major public health concern.
Muhammad Omer Iqbal, Renata Kontek, Abdulmutalib A. Allaq, Montaha Mohamed Ibrahim Mohamed, Muhanad A. Abdulsamad, Esam Bashir Yahya, Summya Rashid, Mateusz Kciuk   +7 more
core   +1 more source

Recent Progress in Dendritic Cell-Based Cancer Immunotherapy

, 2021
Cancer immunotherapy aims to treat cancer by enhancing cancer-specific host immune responses. Recently, cancer immunotherapy has been attracting much attention because of the successful clinical application of immune checkpoint inhibitors targeting the ...
Kazuhiko Matsuo, Osamu Yoshie, Kosuke Kitahata, Yuta Hara, Takashi Nakayama, Momo Kamei   +5 more
core   +1 more source

Biomarkers in Cancer Immunotherapy [PDF]

Cancer Cell, 2015
Antibodies against T cell checkpoint molecules have started to revolutionize cancer treatment. Nevertheless, less than half of all patients respond to these immunotherapies. Recent work supports the potential value of biomarkers that predict therapy outcome and inspires the development of assay systems that interrogate other aspects of the cancer ...
Schumacher, Ton N, Kesmir, Can, van Buuren, Marit M   +2 more
openaire   +4 more sources

Cancer Immunotherapy

Molecular Oncology, 1999
The remarkable specificity of the immune system through antigen recognition has long attracted investigators to the possibility of immune‐based therapy for cancer. Previous cancer immunotherapeutics had been restricted to non‐specific immunomodulatory agents, such as the cytokines IL‐2 or IFN‐α.
openaire   +3 more sources

Cancer Immunotherapy and Application of Nanoparticles in Cancers Immunotherapy as the Delivery of Immunotherapeutic Agents and as the Immunomodulators

, 2020
In the last few decades, cancer immunotherapy becomes an important tactic for cancer treatment. However, some immunotherapy shows certain limitations including poor therapeutic targeting and unwanted side effects that hinder its use in clinics. Recently,
Tilahun Ayane Debele, Wen-Pin Su, Cheng-Fa Yeh   +2 more
core   +1 more source

A rare population of tumor antigen-specific CD4+CD8+ double-positive αβ T lymphocytes uniquely provide CD8-independent TCR genes for engineering therapeutic T cells

Journal for ImmunoTherapy of Cancer, 2019
Background High-affinity tumor antigen-specific T-cell receptor (TCR) gene is required to engineer potent T cells for therapeutic treatment of cancer patients.
Junko Matsuzaki, Takemasa Tsuji, Thinle Chodon, Courtney Ryan, Richard C. Koya, Kunle Odunsi   +5 more
doaj   +1 more source

Developments in Cancer Immunotherapy [PDF]

Digestive Diseases, 2010
Significant advances have been made in the field of cancer immunology and immunotherapy over the last three decades. An important step forward was the identification of human cancer antigens eliciting spontaneous immune responses in cancer patients. The most immunogenic human cancer antigens known to date belong to the cancer-testis family of antigens,
van den Broek, M, von Boehmer, L, Knuth, A   +2 more
openaire   +3 more sources