Results 31 to 40 of about 3,645,426 (307)
Immune mediators as predictive biomarkers for anti-PD-1 antibody therapy in urothelial carcinoma
Frontiers in Pharmacology, 2023 Introduction: This study aimed to identify immune mediators, including cytokines, chemokines, and growth factors, in the plasma for predicting treatment efficacy and immune-related adverse events (irAEs) in advanced urothelial carcinoma (aUC) treated ...
Yosuke Shibata +16 more
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, 2020 In the last few decades, cancer immunotherapy becomes an important tactic for cancer treatment. However, some immunotherapy shows certain limitations including poor therapeutic targeting and unwanted side effects that hinder its use in clinics. Recently,
Tilahun Ayane Debele +2 more
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European Journal of Pharmacology, 2009 Major advances have been made in the field of immunology in the past two decades. A better understanding of the molecular and cellular mechanisms controlling the immune system has opened the door to many innovative and promising new cancer therapies that manipulate the immune response.
Hossein, Borghaei +2 more
openaire +2 more sources
The Renewal of Cancer Immunotherapy
, 2023 Cancer immunotherapy embraces many current, promising therapeutic approaches to eradicate tumors by activating host antitumor activity [...
Jenny Bulgarelli +7 more
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, 2020 Immunotherapy is now widely established as a potent and effective treatment option across several types of cancer. However, there is increasing recognition that not all patients respond to immunotherapy, focusing attention on the immune contexture of the
Spranger-Zimmermann, Stefani
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Transcription factors in fibroblast plasticity and CAF heterogeneity
Journal of Experimental & Clinical Cancer Research, 2023 In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro ...
Roberta Melchionna +4 more
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The Influence of the Microbiome on Immunotherapy for Gastroesophageal Cancer
, 2023 Immunotherapy has shown promise as a treatment option for gastroesophageal cancer, but its effectiveness is limited in many patients due to the immunosuppressive tumor microenvironment (TME) commonly found in gastrointestinal tumors.
Neda Dadgar +3 more
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, 2022 Simple Summary Photothermal therapy (PTT) has become effective through the development of nanoparticle-based photoabsorbers with various functions, such as targeting properties, high light-to-heat conversion, and photostability. Conventional nanoparticle-
Yun, Wan Su +11 more
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Biomarkers in Cancer Immunotherapy [PDF]
Cancer Cell, 2015 Antibodies against T cell checkpoint molecules have started to revolutionize cancer treatment. Nevertheless, less than half of all patients respond to these immunotherapies. Recent work supports the potential value of biomarkers that predict therapy outcome and inspires the development of assay systems that interrogate other aspects of the cancer ...
Schumacher, Ton N +2 more
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Molecular Oncology, 1999 The remarkable specificity of the immune system through antigen recognition has long attracted investigators to the possibility of immune‐based therapy for cancer. Previous cancer immunotherapeutics had been restricted to non‐specific immunomodulatory agents, such as the cytokines IL‐2 or IFN‐α.
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