Results 31 to 40 of about 1,025,329 (302)
Cancer stem cell metabolism [PDF]
Breast Cancer Research, 2016 Cancer is now viewed as a stem cell disease. There is still no consensus on the metabolic characteristics of cancer stem cells, with several studies indicating that they are mainly glycolytic and others pointing instead to mitochondrial metabolism as their principal source of energy.
Peiris-Pagès, M +4 more
openaire +3 more sources
Epigenetics, 2018 The relationship between CpG content and DNA methylation has attracted considerable interest in recent years. Direct or indirect methods have been developed to investigate their regulatory functions based on various hypotheses, large cohort studies, and ...
Fushun Chen +14 more
doaj +1 more source
Brief report: RRx-001 is a c-Myc inhibitor that targets cancer stem cells. [PDF]
, 2018 The goal of anticancer therapy is to selectively eradicate all malignant cells. Unfortunately for the majority of patients with metastatic disease, this goal is consistently thwarted by the nearly inevitable development of therapeutic resistance; the ...
Cabrales, Pedro +5 more
core +2 more sources
Stem Cell Research, 2022 Induced pluripotent stem cell (iPSC) line SCIKFi001-A was reprogrammed from cGMP grade umbilical cord derived mesenchymal stem cells (UC-MSCs) via non-integrating, virus free, self-replicating RNA for eventual use in regenerative medicine.
Ricky Sanjaya +6 more
doaj +1 more source
A Genetically Engineered Oncolytic Adenovirus Decoys and Lethally Traps Quiescent Cancer Stem-like Cells in S/G(2)/M Phases [PDF]
, 2013 Purpose: Because chemoradiotherapy selectively targets proliferating cancer cells, quiescent cancer stem-like cells are resistant. Mobilization of the cell cycle in quiescent leukemia stem cells sensitizes them to cell death signals.
Fujiwara, Toshiyoshi +12 more
core +1 more source
Journal of Translational Medicine, 2017 Background Standardized animal-free components are required for manufacturing cell-based medicinal products. Human platelet concentrates are sources of growth factors for cell expansion but such products are characterized by undesired variability ...
Francesco Agostini +8 more
doaj +1 more source
Chemical approaches to targeting drug resistance cancer stem cells [PDF]
, 2016 STEMCHEM is a COST action aiming to target causes of drug resistance in cancer stem cells. Cancer stem cells are cells which are believed to be responsible for the larger part of the regenerative capacity of cancers.
Blaire Theuma, Krystle +6 more
core +1 more source
Reprogramming Cancer Stem Cells [PDF]
Journal of Cancer Science & Therapy, 2012 n ...
Marco Tafani, Matteo Antonio Russo
openaire +2 more sources
New insights from the widening homogeneity perspective to target intratumor heterogeneity
Cancer Communications, 2018 Precision medicine has shed new light on the treatment of heterogeneous cancer patients. However, intratumor heterogeneity strongly constrains the clinical benefit of precision medicine.
Mengying Tong +6 more
doaj +1 more source
Gastric Cancer Stem Cells [PDF]
Journal of Clinical Oncology, 2008 Cancer stem cells are defined as the unique subpopulation in the tumors that possess the ability to initiate tumor growth and sustain self-renewal as well as metastatic potential. Accumulating evidence in recent years strongly indicate the existence of cancer stem cells in solid tumors of a wide variety of organs.
Shigeo, Takaishi +2 more
openaire +2 more sources