The cancer stem cell marker CD133 interacts with plakoglobin and controls desmoglein-2 protein levels. [PDF]
PLoS ONE, 2013 The pentaspan membrane glycoprotein CD133 (also known as prominin-1) has been widely used as a marker for both cancer and normal stem cells. However, the function of CD133 has not been elucidated. Here we describe a cancer stem cell line established from
Ryo Koyama-Nasu +13 more
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The Expanding Role of Cancer Stem Cell Marker ALDH1A3 in Cancer and Beyond. [PDF]
Cancers (Basel), 2023 McLean ME +8 more
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Multiple lineages of human breast cancer stem/progenitor cells identified by profiling with stem cell markers. [PDF]
PLoS ONE, 2009 Heterogeneity of cancer stem/progenitor cells that give rise to different forms of cancer has been well demonstrated for leukemia. However, this fundamental concept has yet to be established for solid tumors including breast cancer. In this communication,
Wendy W Hwang-Verslues +12 more
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High expression of hTERT and stemness genes in BORIS/CTCFL positive cells isolated from embryonic cancer cells. [PDF]
PLoS ONE, 2014 BORIS/CTCFL is a member of cancer testis antigen family normally expressed in germ cells. In tumors, it is aberrantly expressed although its functions are not completely well-defined. To better understand the functions of BORIS in cancer, we selected the
Loredana Alberti +4 more
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Prominin-1 (CD133) defines both stem and non-stem cell populations in CNS development and gliomas. [PDF]
PLoS ONE, 2014 Prominin-1 (CD133) is a commonly used cancer stem cell marker in central nervous system (CNS) tumors including glioblastoma (GBM). Expression of Prom1 in cancer is thought to parallel expression and function in normal stem cells.
Karl Holmberg Olausson +6 more
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Clinicopathologic and prognostic significance of LGR5, a cancer stem cell marker in patients with colorectal cancer. [PDF]
Colorectal Cancer, 2019 Ihemelandu C +7 more
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Molecules, 2020 The pharmacological effects of BST204—a fermented ginseng extract—on several types of cancers have been reported. However, the effects of ginseng products or single ginsenosides against cancer stem cells are still poorly understood.
Jong Woo Park +2 more
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ICAM1 Is a Potential Cancer Stem Cell Marker of Esophageal Squamous Cell Carcinoma. [PDF]
PLoS ONE, 2015 Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of esophageal cancer diagnosed in Asian countries, with its incidence on the rise. Cancer stem cell (CSC; also known as tumor-initiating cells, TIC) is inherently resistant to cytotoxic ...
Sheng-Ta Tsai +5 more
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Journal of Ovarian Research, 2011 Background Recent evidence has suggested that the capability of cancer to grow, propagate and relapse after therapy is dependent on a small subset of the cell population within the tumor, called cancer stem cells.
Ponnusamy Moorthy P +4 more
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Ganglioside GD2 is a potential candidate marker for lung cancer stem cells [PDF]
Jichu yixue yu linchuang, 2023 Objective To explore the feasibility of ganglioside GD2 as a marker for lung cancer stem cells (LCSCs). Methods Cancer stem cells (CSCs) of lung cancer cell lines were enriched by spheroid culturing in vitro; The expression of stemness-related genes ...
LI Zhen, DUAN Zhaojun, LUO Yunping
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