Results 41 to 50 of about 2,801,613 (361)
Transfection of hPSC-Cardiomyocytes Using Viafect™ Transfection Reagent
Methods and Protocols, 2020 Twenty years since their first derivation, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have shown promise in disease modelling research, while their potential for cardiac repair is being investigated.
Sara E. Bodbin +2 more
doaj +1 more source
Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells
Molecular Cancer, 2017 BackgroundThe initiation and progression of malignant tumors is driven by distinct subsets of tumor-initiating or cancer stem-like cells (CSCs) which develop therapy/apoptosis resistance and self-renewal capacity.
C. Melzer +4 more
semanticscholar +1 more source
Breast cancer stem cells [PDF]
The International Journal of Biochemistry & Cell Biology, 2012 Breast cancer stem cells (BCSCs) constitute a subpopulation of tumor cells that express stem cell-associated markers and have a high capacity for tumor generation in vivo. Identification of BCSCs from tumor samples or breast cancer cell lines has been based mainly on CD44(+)/CD24(-/low) or ALDH(+) phenotypes. BCSCs isolation has allowed the analysis of
Marco A, Velasco-Velázquez +3 more
openaire +2 more sources
Targeting Cancer Stem Cells to Overcome Therapy Resistance in Ovarian Cancer
Cells, 2020 Ovarian cancer is the most lethal gynecological malignancy due to its late detection and high recurrence rate. Resistance to conventional platinum-based therapies and metastasis are attributed to a population of cells within tumors called cancer stem ...
S. Muñoz-Galván, A. Carnero
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The pediatric hematology‐oncology fellowship training curriculum has not substantially changed since its inception. The first year of training is clinically focused, and the second and third years are devoted to scholarship. However, this current structure leaves many fellows less competitive in the current job market, resulting in ...
Scott C. Borinstein +3 more
wiley +1 more source
Cancer stem cells: the lessons from pre‐cancerous stem cells [PDF]
Journal of Cellular and Molecular Medicine, 2007 Introduction Stem cells and cancer stem cells Development of pre‐cancerous and cancer stem cells Characteristics of pre‐cancerous versuscancer stem cells Are there demarcations between pre‐cancerous and cancer stem cells Contribution of pre‐cancerous and cancer stem cells to tumour malignancy Clonal evolution underlies the development of tumour ...
openaire +2 more sources
Breast Cancer Research, 2018 Background Breast cancer (BC) is a heterogeneous disease characterised by variant biology and patient outcome. The amino acid transporter, SLC7A5, plays a role in BC although its impact on patient outcome in different BC subtypes remains to be validated.
Rokaya El Ansari +7 more
doaj +1 more source
Cancer stem cells as key drivers of tumour progression
Journal of Biomedical Sciences, 2018 BackgroundCancer stem cells (CSCs) are subpopulations of cancer cells sharing similar characteristics as normal stem or progenitor cells such as self-renewal ability and multi-lineage differentiation to drive tumour growth and heterogeneity.
Ain Zubaidah Ayob, T. S. Ramasamy
semanticscholar +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine +10 more
wiley +1 more source
, 2021 AbstractCancer stem cells (CSCs), also known as tumorinitiating cells (TICs), are a group of cells found within cancer cells. Like normal stem cells, CSCs can proliferate, engage in self-renewal, and are often implicated in the recurrence of tumors after therapy [1, 2].
Fidelia B, Alvina +2 more
openaire +2 more sources