Results 41 to 50 of about 3,487,182 (349)

RAD50 deficiency is a predictor of platinum sensitivity in sporadic epithelial ovarian cancers

Molecular Biomedicine, 2020
Intrinsic or acquired resistance seriously limits the use of platinating agents in advanced epithelial ovarian cancers. Increased DNA repair capacity is a key route to platinum resistance.
Adel Alblihy, Muslim L. Alabdullah, Michael S. Toss, Mashael Algethami, Nigel P. Mongan, Emad A. Rakha, Srinivasan Madhusudan   +6 more
doaj   +1 more source

Lack of correlation of stem cell markers in breast cancer stem cells [PDF]

, 2014
BACKGROUND: Various markers are used to identify the unique sub-population of breast cancer cells with stem cell properties. Whether these markers are expressed in all breast cancers, identify the same population of cells, or equate to therapeutic ...
A M Thompson, AM Thompson, C Calabrese, C Ginestier, C Scheel, C Sheridan, CE Eyler, CL Chaffer, CM Fillmore, E Charafe-Jauffret, E Resetkova, EY Tan, F Vaillant, G Farnie, G Kristiansen, G Rappa, H Harrison, H Korkaya, J Stingl, J Zhou, JC Lawson, JM Rosen, K Engelmann, K He, K Murray, M Al-Hajj, M Boylan, M Christgen, M Kok, M Pajic, M V Appleyard, MA Ahmed, ME Prince, MH Wright, MJ Grimshaw, MV Appleyard, O Al-Assar, O Leis, O Moussa, P J Coates, P Kabos, R Nenutil, S Bao, S Liu, SY Kim, SY Park, T Tanei, TM Phillips, WW Hwang-Verslues, Y Liu   +49 more
core   +4 more sources

Phospho-protein Analysis in Adherent Cells Using Flow Cytometry

Bio-Protocol, 2019
Protein phosphorylation is one of the most important post-translational modifications, which acts as a reversible on or off switch for the activity of a large number of proteins.
Renu Sharma, Amit Sharma, Atul Kumar, Bithiah Jaganathan   +3 more
doaj   +1 more source

Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations

Haematologica, 2020
Hematopoietic stem cells are responsible for life-long blood cell production and are highly sensitive to exogenous stresses. The effects of low doses of ionizing radiations on radiosensitive tissues such as the hematopoietic tissue are still unknown ...
Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli   +9 more
doaj   +1 more source

Controlling the Bureaucracy of the Antipoverty Program [PDF]

, 1966
Rapid progress made in various areas of regenerative medicine in recent years occurred both at the cellular level, with the Nobel prize-winning discovery of reprogramming (generation of induced pluripotent stem (iPS) cells) and also at the biomaterial ...
Abounit, Armstrong, Auernheimer, Bae, Banito, Banito, Bao, Bass, Basu-Roy, Beier, Ben-Porath, Binyamin, Bitarte, Booth, Brand, Cantz, Cao, Case, Chappell, Chen, Chen, Chen, Chiou, Chylicki, Cobaleda, de Cremoux, Denishefsky, Dickinson, Doi, Eberhard, Egler, Eshghi, Esteban, Evans, Fagin, Feinstein, Feng, Feng, Fimia, Fusaki, Galli, Ghavami, Ghavami, Ghavami, Ghavami, Ghule, Girouard, Godar, Gore, Guo, Guo, Gustafsson, Hanada, Hanley, Hanna, Harper, Hauff, Hellebrekers, Hench, Hench, Hench, Hockemeyer, Hoffmeyer, Hong, Hotta, Hu, Huang, Jain, Jangamreddy, Jangamreddy, Jeter, Jia, Jia, Jia, Junttila, Kaji, Kang, Karimi-Busheri, Kawamura, Kharas, Kim, Kim, Kochhar, Kumar, Lafontan, Lee, Lefebvre, Lengerke, Li, Li, Liu, Liu, Maddika, Marchetto, Marion, Matsuoka, Matsuura, Menendez, Menendez, Mikkelsen, Miller, Miura, Mizuno, Moawad, Momcilovic, Mortensen, Nadiminty, Nagata, Nakagawa, Nakagawa, Nakatogawa, Neumann, Okita, Okita, Okita, Oliver, Parry, Patel, Peng, Place, Plews, Prigione, Ravikumar, Reya, Ribatti, Rius, Rotter, Rowland, Rubinsztein, Ruoslahti, Räisänen, Sabisz, Saigusa, Salemi, Sato, Schenke-Layland, Shan, Singh, Singh, Sommer, Sridharan, Stadtfeld, Stolzenburg, Suhr, Suo, Takahashi, Tirino, Tsai, Tsaousi, Uchino, Vafa, van den Berg, van Tuyn, Vazquez, Vessoni, Vierbuchen, Vincent, Viswanathan, Viswanathan, Wang, Warren, Wary, Wernig, West, Wiechec, Wiechec, Wilmut, Woltjen, Wu, Xynos, Yamanaka, Yang, Yoshida, Yoshimori, Yu, Zbinden, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zheng, Zhou, Zreiqat   +184 more
core   +4 more sources

Cancer stem cell surface markers on normal stem cells

BMB Reports, 2017
The cancer stem cell (CSC) hypothesis has captured the attention of many scientists. It is believed that elimination of CSCs could possibly eradicate the whole cancer.
W. Kim, C. Ryu
semanticscholar   +1 more source

PTEN, Stem Cells, and Cancer Stem Cells [PDF]

Journal of Biological Chemistry, 2009
Like normal stem cells, "cancer stem cells" have the capacity for indefinite proliferation and generation of new cancerous tissues through self-renewal and differentiation. Among the major intracellular signaling pathways, WNT, SHH, and NOTCH are known to be important in regulating normal stem cell activities, and their alterations are associated with ...
Reginald, Hill, Hong, Wu
openaire   +2 more sources

Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. [PDF]

, 2019
Tumor cells harboring stem-like/cancer stem cell (CSC) properties have been identified and isolated from numerous hematological and solid malignancies.
Ames, Erik, Bouzid, Lyes A, Canter, Robert J, Darrow, Morgan A, Grossenbacher, Steven K, Judge, Sean J, Luna, Jesus I, Murphy, William J, Sturgill, Ian R   +8 more
core   +1 more source

Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis

Genes and Diseases, 2018
As the most commonly occurring cancer in women worldwide, breast cancer poses a formidable public health challenge on a global scale. Breast cancer consists of a group of biologically and molecularly heterogeneous diseases originated from the breast ...
Yixiao Feng, Mia Spezia, Shifeng Huang, Chengfu Yuan, Z. Zeng, Linghuan Zhang, Xiaojuan Ji, Wei Liu, Bo Huang, Wenping Luo, Bo Liu, Yan Lei, Scott Du, Akhila Vuppalapati, H. Luu, R. Haydon, T. He, G. Ren   +17 more
semanticscholar   +1 more source

Prostate Stem Cells and Cancer Stem Cells [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
Stem/progenitor cells play central roles in processes of organogenesis and tissue maintenance, whereas cancer stem cells (CSCs) are thought to drive tumor malignancy. Here, we review recent progress in the identification and analysis of normal prostate stem/progenitor cells as well as putative CSCs in both genetically engineered mouse models as well as
Jia J, Li, Michael M, Shen
openaire   +2 more sources