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Mechanical and Systems Biology of Cancer [PDF]
Computational and Structural Biotechnology Journal, 2018 Mechanics and biochemical signaling are both often deregulated in cancer, leading to increased cell invasiveness, proliferation, and survival. The dynamics and interactions of cytoskeletal components control basic mechanical properties, such as cell ...
Fabian Spill, Chris Bakal, Michael Mak
doaj +10 more sources
Editorial: Cancer systems biology [PDF]
Frontiers in Genetics, 2022 Jesús Espinal-Enríquez +3 more
doaj +4 more sources
Precision medicine driven by cancer systems biology. [PDF]
Cancer Metastasis Rev, 2017 Molecular insights from genome and systems biology are influencing how cancer is diagnosed and treated. We critically evaluate big data challenges in precision medicine. The melanoma research community has identified distinct subtypes involving chronic sun-induced damage and the mitogen-activated protein kinase driver pathway.
Filipp FV.
europepmc +8 more sources
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. [PDF]
Front Oncol, 2021 Gondal MN, Chaudhary SU.
europepmc +3 more sources
Accelerating cancer systems biology research through Semantic Web technology. [PDF]
Wiley Interdiscip Rev Syst Biol Med, 2013 Wang Z +4 more
europepmc +3 more sources
Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma. [PDF]
Sci Rep, 2015 Guan J, Gupta R, Filipp FV.
europepmc +3 more sources
An Introduction to the Mathematical Modeling in the Study of Cancer Systems Biology. [PDF]
Cancer Inform, 2018 Alameddine AK, Conlin F, Binnall B.
europepmc +3 more sources
iScience, 2021 Summary: Hypoxia is a critical factor in solid tumors that has been associated with cancer progression and aggressiveness. We recently developed a hypoxia fate mapping system to trace post-hypoxic cells within a tumor for the first time.
Heber L. Rocha +7 more
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iScience, 2021 Summary: We aimed to identify triple-negative breast cancer (TNBC) drivers that regulate survival time as predictive signatures that improve TNBC prognostication.
Courtney D. Dill +4 more
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Development of OX40 agonists for canine cancer immunotherapy
iScience, 2022 Summary: Recent breakthroughs in cancer immunotherapy have provided unprecedented clinical benefits to human cancer patients. Cancer is also one of the most common causes of death in pet dogs.
Damien Ruiz +10 more
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