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Editorial: Cancer systems biology [PDF]
Jesús Espinal-Enríquez+3 more
doaj +4 more sources
Cancer systems biology: exploring cancer-associated genes on cellular networks [PDF]
Genomic alterations lead to cancer complexity and form a major hurdle for a comprehensive understanding of the molecular mechanisms underlying oncogenesis. In this review, we describe the recent advances in studying cancer-associated genes from a systems biological point of view. The integration of known cancer genes onto protein and signaling networks
Edwin Wang+2 more
arxiv +3 more sources
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. [PDF]
Gondal MN, Chaudhary SU.
europepmc +3 more sources
Accelerating cancer systems biology research through Semantic Web technology. [PDF]
Wang Z+4 more
europepmc +3 more sources
Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma. [PDF]
Guan J, Gupta R, Filipp FV.
europepmc +3 more sources
An Introduction to the Mathematical Modeling in the Study of Cancer Systems Biology. [PDF]
Alameddine AK, Conlin F, Binnall B.
europepmc +3 more sources
Background Genetic alterations of somatic cells can drive non-malignant clone formation and promote cancer initiation. However, the link between these processes remains unclear and hampers our understanding of tissue homeostasis and cancer development ...
Lisa Dressler+15 more
doaj +1 more source
The discovery and characterization of antigen-specific CD8+ T cell clonotypes typically involves the labor-intensive synthesis and construction of peptide-MHC tetramers.
William Chour+24 more
doaj +1 more source
The Network of Cancer Genes (NCG) is a manually curated repository of 2372 genes whose somatic modifications have known or predicted cancer driver roles.
Dimitra Repana+8 more
doaj +1 more source
Summary: Hypoxia is a critical factor in solid tumors that has been associated with cancer progression and aggressiveness. We recently developed a hypoxia fate mapping system to trace post-hypoxic cells within a tumor for the first time.
Heber L. Rocha+7 more
doaj