Results 101 to 110 of about 1,972,453 (318)

Photodynamic therapy for cancer of the pancreas

, 2002
Background: Few pancreatic cancers are suitable for surgery and few respond to chemoradiation. Photodynamic therapy produces local necrosis of tissue with light after prior administration of a photosensitising agent, and in experimental studies can be ...
Lovat, L.B., Hatfield, A.W.R., Rogowska, A.Z., Wyld, P., Gillams, A., Jones, L., Bown, S.G., Ripley, P., Whitelaw, D.E., Lees, W.R.   +9 more
core  

Photodynamic Therapy: Targeting Cancer Biomarkers for the Treatment of Cancers

, 2021
Photodynamic therapy (PDT) is a well-documented therapy that has emerged as an effective treatment modality of cancers. PDT utilizes harmless light to activate non- or minimally toxic photosensitizers to generate cytotoxic species for malignant cell ...
James P. Basilion, Dong Luo, Xinning Wang   +2 more
core   +1 more source

Radiopharmaceuticals for Relapsed or Refractory Ovarian Cancers

Frontiers in Oncology, 2019
Targeted radiopharmaceuticals for therapeutic use deliver radionuclides directly to tumor anywhere in the body, and therefore, have renewed interest for clinical development in women with disseminated chemorefractory ovarian cancers.
Charles A. Kunos, Jacek Capala, Shanda Finnigan, Gary L. Smith, Susan Percy Ivy   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A qualitative study evaluating experiences of a lifestyle intervention in men with prostate cancer undergoing androgen suppression therapy [PDF]

, 2012
Background - The severe iatrogenic hypogonadal state induced by medical castration used for treatment of prostate cancer is associated with adverse effects including fatigue, increased fracture risk, and a decrease in skeletal muscle function, which ...
Saxton John M, Nanton Veronica, Helen Crank, Rosario, DJ, Sohanpal, R, Bourke, Liam, John M Saxton, Crank, H., Saxton, John, Bourke Liam, Crank, Helen, Liam Bourke, Saxton, J.M., Nanton, Veronica, Crank Helen, Rosario, D.J., Saxton, John M., Ratna Sohanpal, Sohanpal, Ratna, Saxton, JM, Nanton, V., Bourke, L, Nanton, V, Rosario, Derek J., Sohanpal Ratna, Rosario Derek J, Rosario, D, Derek J Rosario, Veronica Nanton, Crank, H, Bourke, L., Sohanpal, R.   +31 more
core   +1 more source

Proton Beam Therapy for Esophageal Cancer

, 2022
SIMPLE SUMMARY: Early-stage esophageal cancer is managed surgically, with the addition of radiotherapy for locally advanced disease. Current photon-based radiotherapy results in a high treatment-related complications, due to proximal organ involvement ...
Dee, Edward Christopher, Wo, Jennifer Y., Jennifer Y. Wo, Solidum, Jea Giezl N., Raniv D. Rojo, Rojo, Raniv D., Jea Giezl N. Solidum, Edward Christopher Dee   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prognostic significance of a negative PSMA PET/CT in biochemical recurrence of prostate cancer

Cancer Imaging
Background Prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) is becoming standard of care for men with biochemical recurrence (BCR) of prostate cancer.
Sara Harsini, Patrick Martineau, Sonia Plaha, Heather Saprunoff, Catherine Chen, Julia Bishop, Scott Tyldesley, Don Wilson, François Bénard   +8 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dosimetric impact of mixed-energy volumetric modulated arc therapy plans for high-risk prostate cancer

, 2013
Purpose: This study investigated the dosimetric impact of mixing low and high energy treatment plans for prostate cancer treated with volumetric modulated arc therapy (VMAT) technique in the form of RapidArc.Methods: A cohort of 12 prostate cases ...
Pokharel, Shyam; Department of Medical Physics, Premier Oncology, Florida, USA.
core   +1 more source