Results 31 to 40 of about 6,963,646 (317)

Cardiotoxicity and Cancer Therapy [PDF]

open access: yesAngiology, 2013
A fundamental concept of treatment is to do no harm. However, with cancer treatment this is not always possible. Chemotherapy is associated with cardiovascular (CV) complications.1,2 This risk is even greater in the elderly patients and patients with established CV disease.
Vasiliadis, I   +2 more
openaire   +3 more sources

An immunogenic first-in-human immune modulatory vaccine with PD-L1 and PD-L2 peptides is feasible and shows early signs of efficacy in follicular lymphoma

open access: yesOncoImmunology, 2021
Cells in the tumor microenvironment of Follicular lymphoma (FL) express checkpoint molecules such as programmed death ligands 1 and 2 (PD-L1 and PD-L2) and are suppressing anti-tumor immune activity.
Uffe Klausen   +18 more
doaj   +1 more source

Node-positive breast cancer: Which are the best chemotherapy regimens? [PDF]

open access: yes, 2008
Breast cancer-associated mortality has been significantly reduced since the 1990s, mainly because of early diagnosis and systemic therapeutic interventions.
Bauerfeind, Ingo   +6 more
core   +1 more source

Results of Radiation Therapy as Local Ablative Therapy for Oligometastatic Non-Small Cell Lung Cancer

open access: yes, 2021
Oligometastatic cancer is characterized by a limited number of metastatic deposits. Compared with lung cancer patients who have more widespread disease, oligometastatic lung cancer patients have more favorable survival outcomes.
David L. Billing, Andreas Rimner
core   +1 more source

Impact of heterogeneities on lateral penumbra in uniform scanning proton therapy [PDF]

open access: yes, 2013
Purpose: In the treatment planning of uniform scanning proton therapy, an aperture block is designed for each beam with a margin, which typically includes the lateral penumbra measured in water (homogenous) medium.
Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City   +1 more
core   +1 more source

Intensity modulated radiotherapy versus volumetric modulated arc therapy in breast cancer: A comparative dosimetric analysis [PDF]

open access: yes, 2015
Purpose: Intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) has the capacity to optimize the dose distribution. We analyzed the dosimetric differences of plans in treatment planning system (TPS) between VMAT and IMRT in ...
Soubhagya, Bhudevi; Basavataram Indo-American Cancer Institute and Research center, Hyderabad   +2 more
core   +1 more source

Neutrophil Extracellular Traps in Cancer Therapy Resistance

open access: yes, 2022
Neutrophils and their products are increasingly recognized to have a key influence on cancer progression and response to therapy. Their involvement has been shown in nearly every aspect of cancer pathophysiology with growing evidence now supporting their
Jonathan J. Cools-Lartigue   +7 more
core   +1 more source

Non-chemotherapy adjuvant agents in TP53 mutant Ewing sarcoma

open access: yesScientific Reports, 2023
Ewing sarcoma (EWS) is a malignant tumor arising in bone or soft tissue that occurs in adolescent and young adult patients as well as adults later in life.
Jin-Ah Kim   +11 more
doaj   +1 more source

Role of ultraviolet mutational signature versus tumor mutation burden in predicting response to immunotherapy

open access: yesMolecular Oncology, 2020
Hydrophobic neoantigens are more immunogenic because they are better presented by the major histocompatibility complex and better recognized by T cells. Tumor cells can evade the immune response by expressing checkpoints such as programmed death ligand 1.
Timothy V. Pham   +6 more
doaj   +1 more source

Quality management in radiation therapy: A 15 year review of incident reporting in two integrated cancer centres

open access: yesTechnical Innovations & Patient Support in Radiation Oncology, 2020
Fifteen years of reported incidents were reviewed to provide insight into the effectiveness of an Incident Learning System (ISL). The actual error rate over the 15 years was 1.3 reported errors per 1000 treatment attendances.
Sandie Smith   +8 more
doaj   +1 more source

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