Results 31 to 40 of about 1,972,453 (318)

Telomeres in Cancer Therapy

open access: yesBioMed Research International, 2001
Finding new targets to improve current cancer therapies is one of the areas of Biomedicine and Biotechnology that generates greater expectations. The telomeres, special protective structures at the end of eukaryotic chromosomes have been metaphorically proposed to be cancer's Achilles heel, since they are essential to stabilize linear chromosomes [1 ...
openaire   +2 more sources

Antibiotics for cancer therapy

open access: yesOncotarget, 2015
Elegant studies by Lisanti, Sotgia and co-workers demonstrate that when breast cancer cells are grown under conditions that promote 3D-sphere formation, which selects for cancer stem cells, that mitochondrial proteins are dramatically induced. Importantly, these studies also show that antibiotic agents that function as mammalian inhibitors of ...
Pestell, Richard, Rizvanov, Albert A
openaire   +2 more sources

Suboptimal Vitamin D levels among adult survivors of childhood cancers

open access: yes, 2016
Purpose: Vitamin D plays an important role in many bodily systems, with increasing evidence suggesting its importance for the prevention of chronic diseases and cancer.
Lisac, Robert; Department of Pediatric Oncology, Roswell Park Cancer Institute, Buffalo, New York   +4 more
core   +1 more source

Multiparametric magnetic resonance imaging in mucosal primary head and neck cancer: a prospective imaging biomarker study

open access: yesBMC Cancer, 2017
Background Radical radiotherapy, with or without concomitant chemotherapy forms the mainstay of organ preservation approaches in mucosal primary head and neck cancer.
Christopher N Rumley   +7 more
doaj   +1 more source

Dosimetric feasibility of moderately hypofractionated/dose escalated radiation therapy for localised prostate cancer with intensity-modulated proton beam therapy using simultaneous integrated boost (SIB-IMPT) and impact of hydrogel prostate-rectum spacer

open access: yesRadiation Oncology, 2022
Purpose To examine the dosimetric feasibility of hypofractionated/dose escalated radiation therapy in patients with localized prostate carcinoma using simultaneous integrated boost intensity-modulated proton beam therapy (SIB-IMPT) in absence or presence
Dalia Ahmad Khalil   +12 more
doaj   +1 more source

The role of CDK inhibitors in breast cancer therapy

open access: yes, 2016
Cyclin D1 and cyclin-dependent protein kinases CDK4/6 are part of RB-pathway which plays a very important role in the regulation of cell cycle progression and cell death.
Huszno, Joanna; Clinical and Experimental Oncology Department, Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice
core   +1 more source

Chinese Expert Consensus on Oncology Multimorbidity Management (2025 Edition)

open access: yesZhongliu Fangzhi Yanjiu
Against the backdrop of accelerated population aging, the prevalence of comorbidities in patients with malignant tumors has risen by 0.54% annually, presenting a significant challenge to clinical oncology.
Chinese Society of Clinical Oncology (CSCO) Committee of Experts on Cancer Supportive and Rehabilitation Therapy
doaj   +1 more source

Nanoactuators for cancer Therapy

open access: yesProceedings of the Advanced materials and devices for nanomedicine, 2022
The research for this work has received funding from the European Union (EU) project HOTZYMES (grant agreement n° 829162) under EU’s Horizon 2020 Programme Research and Innovation actions H2020-FETOPEN-2018-2019-2020-01. Authors also thank Spanish MINECO project BIO2017-84246-C2-1-R and DGA.
openaire   +2 more sources

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele   +19 more
wiley   +1 more source

Cancer research and therapy: Where are we today?

open access: yes, 2014
Till date scientists are struggling to understand the complete mechanism of carcinogenesis. In future, the real time detection of cancer may help scientists to identify some of the complicated biological mechanisms.
Sawant, Sampada; C.U. Shah College of Pharmacy, SNDT Women’s University, Juhu, Santacruz (West), Mumbai, India   +1 more
core   +1 more source

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