Results 41 to 50 of about 2,928,478 (311)

Cardiotoxicity and Cancer Therapy [PDF]

Angiology, 2013
A fundamental concept of treatment is to do no harm. However, with cancer treatment this is not always possible. Chemotherapy is associated with cardiovascular (CV) complications.1,2 This risk is even greater in the elderly patients and patients with established CV disease.
Vasiliadis, I, Kolovou, G, Mikhailidis, DP   +2 more
openaire   +3 more sources

Dosimetric feasibility of moderately hypofractionated/dose escalated radiation therapy for localised prostate cancer with intensity-modulated proton beam therapy using simultaneous integrated boost (SIB-IMPT) and impact of hydrogel prostate-rectum spacer

Radiation Oncology, 2022
Purpose To examine the dosimetric feasibility of hypofractionated/dose escalated radiation therapy in patients with localized prostate carcinoma using simultaneous integrated boost intensity-modulated proton beam therapy (SIB-IMPT) in absence or presence
Dalia Ahmad Khalil, Danny Jazmati, Dirk Geismar, Jörg Wulff, Christian Bäumer, Paul Heinz Kramer, Theresa Steinmeier, Stefanie Schulze Schleitthoff, Sandija Plaude, Martin Bischoff, Stephan Tschirdewahn, Boris Hadaschik, Beate Timmermann   +12 more
doaj   +1 more source

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]

, 2012
Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Kopp, Florian, Oak, Prajakta S., Roidl, Andreas, Wagner, Ernst   +3 more
core   +3 more sources

Autophagy in Cancer Therapy [PDF]

Frontiers in Oncology, 2017
Autophagy represents a catabolic program involved in the degradation of cellular components via lysosomes. It serves to mitigate cellular stress and to provide metabolic precursors especially upon starvation. Thereby, autophagy can support the survival of cancer cells.
Simone Fulda, Simone Fulda, Simone Fulda
openaire   +5 more sources

Neoadjuvant therapy for breast cancer [PDF]

, 2019
Objective: To evaluate the frequency of neoadjuvant therapy (NT) in women with stage I–III breast cancer in Italy and whether it is influenced by biological characteristics, screening history, and geographic area.
Carrozzi G., Filiberti R. A., Giorgi Rossi P., Iacovacci S., Mancuso P., Mangone L., Mazzucco W., Minicozzi P., Sant M., Tagliabue G., Tumino R.   +10 more
core   +1 more source

Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]

, 2017
Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R., Gompel, Anne, Lumsden, Mary Ann, Pinkerton, JoAnn V., Santen, Richard J., Stuenkel, Cynthia A.   +5 more
core   +1 more source

Chinese Expert Consensus on Oncology Multimorbidity Management (2025 Edition)

Zhongliu Fangzhi Yanjiu
Against the backdrop of accelerated population aging, the prevalence of comorbidities in patients with malignant tumors has risen by 0.54% annually, presenting a significant challenge to clinical oncology.
Chinese Society of Clinical Oncology (CSCO) Committee of Experts on Cancer Supportive and Rehabilitation Therapy
doaj   +1 more source

Improved migration of tumor ascites lymphocytes to ovarian cancer microenvironment by CXCR2 transduction

OncoImmunology, 2018
Chemokines are essential mediators of cellular trafficking, interactions and tumor development. Though adoptive cell therapy (ACT) has been a tremendous success in the treatment of metastatic melanoma (MM), a major obstacle for successful ACT, is limited
Manja Idorn, Maria Olsen, Hólmfrídur Rósa Halldórsdóttir, Signe Koggersbøl Skadborg, Magnus Pedersen, Claus Høgdall, Estrid Høgdall, Özcan Met, Per thor Straten   +8 more
doaj   +1 more source

Multiparametric magnetic resonance imaging in mucosal primary head and neck cancer: a prospective imaging biomarker study

BMC Cancer, 2017
Background Radical radiotherapy, with or without concomitant chemotherapy forms the mainstay of organ preservation approaches in mucosal primary head and neck cancer.
Christopher N Rumley, Mark T Lee, Lois Holloway, Robba Rai, Myo Min, Dion Forstner, Allan Fowler, Gary Liney   +7 more
doaj   +1 more source

Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head

Radiation Oncology, 2020
Background The purpose of this study was to determine the potential of escalated dose radiation (EDR) robust intensity-modulated proton radiotherapy (ro-IMPT) in reducing GI toxicity risk in locally advanced unresectable pancreatic cancer (LAUPC) of the ...
Vijay P. Raturi, Hidehiro Hojo, Kenji Hotta, Hiromi Baba, Ryo Takahashi, Toshiya Rachi, Naoki Nakamura, Sadamoto Zenda, Atsushi Motegi, Hidenobu Tachibana, Takaki Ariji, Kana Motegi, Masaki Nakamura, Masayuki Okumura, Yasuhiro Hirano, Tetsuo Akimoto   +15 more
doaj   +1 more source