Results 121 to 130 of about 334,749 (357)

Tissue vaccines for cancer

Expert Review of Vaccines, 2007
Most tumors, including prostate carcinoma, are heterogeneous mixtures of neoplastic cells and supporting stromal matrix. Attempts to vaccinate as a means to treat or prevent cancer have typically relied on use of a single antigen or cell type. In the case of whole-cell vaccines, clonal populations of cancer cells are grown in culture and harvested for ...
Julie E. Heinrich, Mark A. Suckow, Elliot D. Rosen   +2 more
openaire   +3 more sources

Teenagers’ understandings of and attitudes towards vaccines and vaccine-preventable diseases: a qualitative study [PDF]

, 2013
<p>Background: To examine immunisation information needs of teenagers we explored understandings of vaccination and vaccine-preventable diseases, attitudes towards immunisation and experiences of immunisation.
Barbour, Bedford, Bloor, Bond, Brabin, Brownlie, Butler, Bynum, C. Patterson, Clark, Crocker, Duffell, E. Smith, Finn, Flynn, Gellin, Gordon, H. Bedford, Hilton, Hilton, Hilton, Hinds, Hobson-West, K. Hunt, Kale, Kitzinger, Lashkari, Maple, Marlow, Miller, Paranthaman, Pareek, Parrella, Peckham, Pelucchi, Pollard, Poltorak, Ramsay, Ritchie, S. Hilton, Slonim, Smailbegovic, Smith, Sporton, Streefland, Stretch, Woodhall, Yarwood, Zimet   +48 more
core   +1 more source

Geometric Adjustment of T Cell‐Sensitive Nanorobots for Enhanced Stability

Advanced Healthcare Materials, EarlyView.
For the long‐term use of live dendritic cell (DC)‐based vaccines, nano bone marrow dendritic cell (BMDC) originated T cell activators (nano‐BOTs) are synthesized. The geometric properties of nanoparticles are precisely modulated, enhancing their stability and T cell activation capacity.
Yoojin Lee, Dahae Kim, Taihyun Kim, Chae‐Won Moon, Hyungseok Yong, Sung‐eun Heo, Bumgyu Choi, Yoogyeong Oh, Woojin Choi, Kyungtae Park, Sang‐Jun Ha, Jinkee Hong   +11 more
wiley   +1 more source

Hierarchical hydropathic evolution of influenza glycoproteins (N2, H3, A/H3N2) under relentless vaccination pressure [PDF]

arXiv, 2013
Hemagglutinin (HA) and neuraminidase (NA) are highly variable envelope glycoproteins. Here hydropathic analysis, previously applied to quantify common flu (H1N1) evolution (1934-), is applied to the evolution of less common but more virulent (avian derived) H3N2 (1968-), beginning with N2.
arxiv  

Changes in Knowledge of HPV, Cervical Cancer, PAP Smears, and Attitudes Towards HPV vaccination from a Community-Based Intervention for Latinas

, 2019
Purpose/Background: Latinas are 20% less likely to receive the HPV vaccine and, in Idaho, are 35% more likely to die of cervical cancer than non-Latinas -16.2/100,000 in Latinas vs. 7.6/100,000 non-Latinas-.
Fore, Elizabeth, Phelps, Paula, Tarp, Helen C.   +2 more
core  

Evidence for cross-protection but not type-replacement over the 11 years after human papillomavirus vaccine introduction [PDF]

, 2019
Examination of cross-protection and type replacement after human papillomavirus (HPV) vaccine introduction is essential to guide vaccination recommendations and policies.
Bernstein, David I., Brown, Darron, Covert, Courtney, Ding, Lili, Franco, Eduardo L., Kahn, Jessica A.   +5 more
core   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Human Papillomavirus: How Social Ideologies Influence Medical Policy and Care [PDF]

, 2012
The purpose of this paper is to discuss the ways in which new advances in the production of a vaccine against human papillomavirus (HPV) have been received by both the general public and the medical community.
Hachem, Fadi
core   +1 more source

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial [PDF]

, 2016
Vaccination with priming and expansion of tumour reacting T cells is an important therapeutic option to be used in combination with novel checkpoint inhibitors to increase the specificity of the T cell infiltrate and the efficacy of the treatment. In
Antonilli M, BARCHIESI, GIACOMO, BELLATI, FILIPPO, BENEDETTI PANICI, PIERLUIGI, CAPONNETTO, SALVATORE, Iadarola R, NAPOLETANO, Chiara, NUTI, Marianna, PIERELLI, LUCA, RAHIMI KOSHKAKI, HASSAN, RUGHETTI, Aurelia, RUSCITO, ILARY, VISCONTI, Valeria, ZIZZARI, ILARIA GRAZIA   +13 more
core   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

Advanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou, Johanna Simon, Moritz Beck‐Broichsitter, Gary Davidson, Pavel A. Levkin   +4 more
wiley   +1 more source